Germline stem cells in human

H Cheng, D Shang, R Zhou - Signal transduction and targeted therapy, 2022 - nature.com
The germline cells are essential for the propagation of human beings, thus essential for the
survival of mankind. The germline stem cells, as a unique cell type, generate various states …

The Important Role of Sex-Related Sox Family Genes in the Sex Reversal of the Chinese Soft-Shelled Turtle (Pelodiscus sinensis)

Y Wang, X Luo, C Qu, T Xu, G Zou, H Liang - Biology, 2022 - mdpi.com
Simple Summary Pelodiscus sinensis is an important aquatic economic species in China
with sexual dimorphism. All-male breeding is becoming a research hotspot. Here …

Mucociliary Wnt signaling promotes cilia biogenesis and beating

C Seidl, F Da Silva, K Zhang, K Wohlgemuth… - Nature …, 2023 - nature.com
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile
cilia are signaling-inert nanomotors. Contrasting both views, we here show in the …

The journey of a generation: advances and promises in the study of primordial germ cell migration

LJ Barton, L Roa-de la Cruz, R Lehmann… - Development, 2024 - journals.biologists.com
The germline provides the genetic and non-genetic information that passes from one
generation to the next. Given this important role in species propagation, egg and sperm …

SOX7 inhibits the malignant progression of bladder cancer via the DNMT3B/CYGB axis

J Zhang, W Zhang, J Liu, Y Liu, Y Jiang… - Molecular …, 2024 - Springer
Bladder cancer (BCa) stands out as a highly prevalent malignant tumor affecting the urinary
system. The Sex determining region Y-box protein family is recognized for its crucial role in …

Novel functions of the ubiquitin-independent proteasome system in regulating Xenopus germline development

H Hwang, Z Jin, VV Krishnamurthy, A Saha… - …, 2019 - journals.biologists.com
In most species, early germline development occurs in the absence of transcription with
germline determinants subject to complex translational and post-translational regulations …

Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells

A Turgeon, J Fu, M Ma, Z Jin, H Hwang, M Li… - Developmental …, 2024 - Elsevier
Primordial germ cells (PGCs) are the precursors of sperms and oocytes. Proper
development of PGCs is crucial for the survival of the species. In many organisms, factors …

[PDF][PDF] 中华鳖性别差异表达基因比较研究

周先文, 王晓清, 王佩, 江辉, 曾丹, 彭英海 - 渔业研究, 2021 - hyyysci.com
为获得中华鳘(Trionyx sinensis) 性别差异表达基因, 探索中华鳘性别决定机制, 本研究采用RNA-
Seq 技术测定了中华鳖成熟期精巢和卵巢转录组, 分别获得了21 494 396 400 bp 和24 605 142 …

Generation of no‐yellow‐pigment Xenopus tropicalis by slc2a7 gene knockout

K Nakajima, M Shimamura… - Developmental Dynamics, 2021 - Wiley Online Library
Background Amphibians possess three kinds of dermal chromatophore: melanophores,
iridophores, and xanthophores. Knockout Xenopus tropicalis that lack the pigmentation of …

Expression of the Germes Germ Plasm Gene in Follicular Cells of X. laevis Oocytes

VV Konduktorova, NN Luchinskaya… - Russian Journal of …, 2022 - Springer
During oogenesis, most of the mRNA is localized at the vegetal pole of the oocyte in a
special area called the germ plasm. Germ plasm plays an essential and necessary role in …