Background: Metformin is widely used for management of Type 2 Diabetes Mellitus (T2DM).
Recently growing evidences have shown its anti-cancer effects. The results are mainly from …

The lack of in-depth knowledge about the molecular determinants of glioblastoma (GBM)
occurrence and progression, combined with few effective and BBB crossing-targeted …

Oxidative stress injury is an important link in the pathogenesis of diabetes, and reducing
oxidative stress damage caused by long-term hyperglycemia is an important diabetic …

Introduction To develop and validate a radiogenomics model for predicting axillary lymph
node metastasis (ALNM) in breast cancer compared to a genomics and radiomics model …

Diabetes mellitus (DM) is associated with an increased risk of colorectal cancer (CRC).
Hyperglycemia, a chronic abnormality in diabetes, is an independent predictor of cancer …

INTERMITTENT FASTING BOOSTS NEUROGENIN-3 (NGN3) EXPRESSION AND BETA
CELL NEOGENESIS Several recent studies have found that repeated episodes of fasting (or …

The occurrence and development of diabetes seriously threaten the health of patients.
Therefore, the mechanism exploration of diabetes is of great significance for more effective …

Neovascular age-related macular degeneration (nAMD), a leading cause of blindness in
older adults, presents a challenging pathophysiology involving choroidal neovascularization …

Background The effect of metformin on primary bone cancer risk has not been researched.
This retrospective cohort study investigated the risk of primary bone cancer between …

Lung cancer maintains a relatively small survival rate (~ 19%) over a 5-year period and up to
80–85% of all lung cancer diagnoses are Non-Small Cell Lung Cancer (NSCLC). To …