Pharmacological optimization of PSMA-based radioligand therapy

S van der Gaag, IH Bartelink, AN Vis, GL Burchell… - Biomedicines, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignancy in men of middle and older age. The
standard treatment strategy for PCa ranges from active surveillance in low-grade, localized …

Novel histopathological biomarkers in prostate cancer: implications and perspectives

P Kiełb, K Kowalczyk, A Gurwin, Ł Nowak, W Krajewski… - Biomedicines, 2023 - mdpi.com
Prostate cancer (PCa) is the second most frequently diagnosed cancer in men. Despite the
significant progress in cancer diagnosis and treatment over the last few years, the approach …

Renal and multiorgan safety of 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer in the VISION dosimetry substudy

K Herrmann, K Rahbar, M Eiber, R Sparks… - Journal of Nuclear …, 2024 - Soc Nuclear Med
In the VISION trial,[177Lu] Lu-PSMA-617 (177Lu-PSMA-617) plus protocol-permitted
standard of care significantly improved overall survival and radiographic progression-free …

Biomarkers for the detection and surveillance of renal cancer

JI Nolazco, SJC Soerensen, BI Chung - Urologic Clinics, 2023 - urologic.theclinics.com
Renal cell carcinoma (RCC) is one of the most commonly diagnosed cancers in the United
States. It accounts for approximately 4.0% of new cancers and 2.3% of cancer-specific …

[HTML][HTML] Current and future perspectives on functional molecular imaging in nephro-urology: theranostics on the horizon

Y Toyama, RA Werner, CA Ruiz-Bedoya… - Theranostics, 2021 - ncbi.nlm.nih.gov
In recent years, a paradigm shift from single-photon-emitting radionuclide radiotracers
toward positron-emission tomography (PET) radiotracers has occurred in nuclear oncology …

Characterization of tumor thrombus in renal cell carcinoma with prostate specific membrane antigen (PSMA) positron emission tomography (PET)/computed …

A Tariq, S McGeorge, A Pearce, H Rhee… - … Oncology: Seminars and …, 2022 - Elsevier
Introduction Venous tumor thrombus (TT) occurs as part of the natural history of renal cell
carcinoma (RCC) local progression in a small minority of cases. MRI is currently the most …

[HTML][HTML] The role of prostate-specific membrane antigen positron emission tomography/computed tomography in primary staging of selected renal tumours: initial …

A Tariq, A Pearce, H Rhee, S Kyle… - European Urology …, 2024 - Elsevier
Background Accurate primary staging of renal cancer with conventional imaging is
challenging. Prostate-specific membrane antigen (PSMA) positron emission …

[HTML][HTML] Expression of prostate-specific membrane antigen (PSMA) in papillary renal cell carcinoma-overview and report on a large multicenter cohort

S Zschäbitz, F Erlmeier, C Stöhr, E Herrmann… - Journal of …, 2022 - ncbi.nlm.nih.gov
Prostate specific membrane antigen (PSMA) is an emerging diagnostic and therapeutic
target in prostate cancer. 68 Ga-PSMA-labeled hybrid imaging is used for the detection of …

PSMA PET-CT imaging predicts treatment progression in men with biochemically recurrent prostate cancer—a prospective study of men with 3 year follow up

S Ong, C Pascoe, BD Kelly, Z Ballok, D Webb, D Bolton… - Cancers, 2022 - mdpi.com
Simple Summary Prostate-specific membrane antigen (PSMA) positron emission
tomography-computed tomography (PET-CT) is an essential imaging tool that is used to …

PSMA immunohistochemistry in hepatic neoplasms: a promising diagnostic marker with potential theranostic applications

M Kmeid, YN Park, T Chung, G Lukose… - The American Journal …, 2022 - journals.lww.com
Accurate classification of well-differentiated hepatocellular neoplasms can be challenging
especially in core biopsies. Prostate-specific membrane antigen (PSMA) has been shown to …