The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

In coronavirus disease 2019 (COVID‐19), higher morbidity and mortality are associated with
age, male gender, and comorbidities, such as chronic lung diseases, cardiovascular …

Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), a
widespread disorder of breathing. This Review focuses on the role of hypoxia-inducible …

The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

Hypoxia is a fundamental stimulus that impacts cells, tissues, organs, and physiological
systems. The discovery of hypoxia-inducible factor-1 (HIF-1) and subsequent identification of …

Obstructive sleep apnea (OSA) is characterized by repetitive apnea–hypopnea cycles
during sleep, which are associated with oxygen desaturation and sleep disruption. Up to …

It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial
pressure levels. Sympathetic oscillations coupled to the respiratory activity have been …

There is increasing evidence that intermittent hypoxia plays a role in the development of
cardiovascular risk in obstructive sleep apnoea syndrome (OSAS) through the activation of …