NPY antagonizes behavioral consequences of stress through actions within the brain.
Behavioral anti-stress actions of NPY are noteworthy in that (1) their magnitude surpasses …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

There is evidence that BDNF influences the birth of granule cells in the dentate gyrus, which
is one of the few areas of the brain that demonstrates neurogenesis throughout life …

Neuropepetide Y (NPY) is best known for its powerful stimulation of food intake and its
effects on reducing energy expenditure. However, the pathways involved and the regulatory …

In the CNS, there are widespread and diverse interactions between growth factors and
estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic …

Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

In mammals, new neurons can be generated from neural stem cells in specific regions of the
adult brain. Neural stem cells are characterized by their abilities to differentiate into all …

While it is well known that production of new neurons from neural stem/progenitor cells
(NSC) in the dentate gyrus (DG) diminishes greatly by middle age, the phases and …

The hippocampus is very susceptible to aging. Severely diminished dentate neurogenesis at
middle age is one of the most conspicuous early changes in the aging hippocampus, which …

The neuropeptide Y (NPY) system–comprising of neuropeptide Y, peptide YY, pancreatic
polypeptide and the corresponding Y receptors through which they act (Y1, Y2, Y4, Y5 and …