Colorectal cancer (CRC) disproportionately affects people from low socioeconomic
backgrounds and some racial minorities. Disparities in CRC incidence and outcomes might …

KRAS is the most frequently mutated oncogene in cancer. Following numerous attempts to
inhibit KRAS spanning multiple decades, recent efforts aimed at covalently targeting the …

The occurrence of colorectal cancer (CRC) shows a large disparity among recognized races
and ethnicities in the US, with Black Americans demonstrating the highest incidence and …

Importance Information about stage of cancer at diagnosis, use of therapy, and survival
among patients from different racial/ethnic groups with 1 of the most common cancers is …

Avoidable differences in the care and outcomes of patients with cancer (ie, cancer care
disparities) emerge or worsen with discoveries of new, more effective approaches to cancer …

PURPOSE Comprehensive tumor biomarker testing is a fundamental step in the selection of
highly effective molecularly driven therapies for a variety of solid tumors. The primary …

Importance Disparity in overall survival (OS) and differences in the frequency of driver gene
variants by race and ethnicity have been separately observed in patients with colorectal …

PURPOSE CALGB (Alliance)/SWOG 80405 was a randomized phase III trial that in first-line
patients with metastatic colorectal cancer (mCRC) treated with bevacizumab or cetuximab …

Precision medicine based upon molecular testing is heralded as a revolution in how cancer
is prevented, diagnosed, and treated. Large efforts across the world aim to conduct …

Background/Aim: African Americans (AA) have the highest incidence and mortality of any
racial/ethnic group in the US for most cancer types. Heterogeneity in the molecular biology …