The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans

P Partscht, E Schiebel - The EMBO Journal, 2023 - embopress.org
CDC14, originally identified as crucial mediator of mitotic exit in budding yeast, belongs to
the family of dual‐specificity phosphatases (DUSPs) that are present in most eukaryotes …

The multiple roles of the Cdc14 phosphatase in cell cycle control

J Manzano-López, F Monje-Casas - International Journal of Molecular …, 2020 - mdpi.com
The Cdc14 phosphatase is a key regulator of mitosis in the budding yeast Saccharomyces
cerevisiae. Cdc14 was initially described as playing an essential role in the control of cell …

Cdc14 and PP2A phosphatases cooperate to shape phosphoproteome dynamics during mitotic exit

SA Touati, L Hofbauer, AW Jones, AP Snijders, G Kelly… - Cell reports, 2019 - cell.com
Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate
chromosome segregation and for completion of the cell division cycle during exit from …

A CRISPR/Cas9‐mediated in situ complementation method for Phytophthora sojae mutants

M Qiu, Y Li, W Ye, X Zheng… - Molecular plant …, 2021 - Wiley Online Library
Phytophthora sojae is an important model species for oomycete functional genomics
research. Recently, a CRISPR/Cas9‐mediated genome‐editing technology has been …

A phosphatase‐centric mechanism drives stress signaling response

DM Hollenstein, G Gérecová, N Romanov, J Ferrari… - EMBO …, 2021 - embopress.org
Changing environmental cues lead to the adjustment of cellular physiology by
phosphorylation signaling networks that typically center around kinases as active effectors …

Interplay between phosphatases and the anaphase-promoting complex/cyclosome in mitosis

M Kataria, H Yamano - Cells, 2019 - mdpi.com
Accurate division of cells into two daughters is a process that is vital to propagation of life.
Protein phosphorylation and selective degradation have emerged as two important …

The regulation of Net1/Cdc14 by the Hog1 MAPK upon osmostress unravels a new mechanism regulating mitosis

J Jiménez, E Queralt, F Posas, E de Nadal - Cell Cycle, 2020 - Taylor & Francis
During evolution, cells have developed a plethora of mechanisms to optimize survival in a
changing and unpredictable environment. In this regard, they have evolved networks that …

PP2A functions during mitosis and cytokinesis in yeasts

Y Moyano-Rodriguez, E Queralt - International journal of molecular …, 2019 - mdpi.com
Protein phosphorylation is a common mechanism for the regulation of cell cycle progression.
The opposing functions of cell cycle kinases and phosphatases are crucial for accurate …

[HTML][HTML] Decoding the Nucleolar Role in Meiotic Recombination and Cell Cycle Control: Insights into Cdc14 Function

P Alonso-Ramos, JA Carballo - International Journal of Molecular …, 2024 - mdpi.com
The cell cycle, essential for growth, reproduction, and genetic stability, is regulated by a
complex network of cyclins, Cyclin-Dependent Kinases (CDKs), phosphatases, and …

PP2A-Cdc55 phosphatase regulates actomyosin ring contraction and septum formation during cytokinesis

Y Moyano-Rodríguez, D Vaquero… - Cellular and Molecular …, 2022 - Springer
Eukaryotic cells divide and separate all their components after chromosome segregation by
a process called cytokinesis to complete cell division. Cytokinesis is highly regulated by the …