Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

X Zhao, J Liu, J Fan, H Chao, X Peng - Chemical Society Reviews, 2021 - pubs.rsc.org
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Heavy-atom-free photosensitizers: from molecular design to applications in the photodynamic therapy of cancer

VN Nguyen, Y Yan, J Zhao, J Yoon - Accounts of chemical …, 2020 - ACS Publications
Conspectus Photodynamic therapy (PDT) is a clinically approved therapeutic modality that
has shown great potential for the treatment of cancers owing to its excellent spatiotemporal …

Luminescent radicals

A Mizuno, R Matsuoka, T Mibu, T Kusamoto - Chemical Reviews, 2024 - ACS Publications
Organic radicals are attracting increasing interest as a new class of molecular emitters. They
demonstrate electronic excitation and relaxation dynamics based on their doublet or higher …

Heavy-atom-free BODIPY photosensitizers with intersystem crossing mediated by intramolecular photoinduced electron transfer

MA Filatov - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Organic photosensitizers possessing efficient intersystem crossing (ISC) and forming long-
living triplet excited states, play a crucial role in a number of applications. A common …

Properties and applications of photoexcited chromophore–radical systems

T Quintes, M Mayländer, S Richert - Nature Reviews Chemistry, 2023 - nature.com
Photoexcited organic chromophore–radical systems hold great promise for a range of
technological applications in molecular spintronics, including quantum information …

A self‐degradable supramolecular photosensitizer with high photodynamic therapeutic efficiency and improved safety

B Yuan, H Wu, H Wang, B Tang, JF Xu… - Angewandte …, 2021 - Wiley Online Library
Concerning that the residues of photosensitizers (PS) may cause serious side effects under
light, it is of great significant to timely switch‐off PS after photodynamic therapy (PDT) …

Recent development of heavy-atom-free triplet photosensitizers: molecular structure design, photophysics and application

X Zhang, Z Wang, Y Hou, Y Yan, J Zhao… - Journal of Materials …, 2021 - pubs.rsc.org
Triplet photosensitizers (PSs) have attracted much attention in recent years, due to the
significance of these kinds of compounds in fundamental photochemistry studies and …

Near-infrared photosensitizers adaptive to tumor hypoxic microenvironment for synergistic photothermal-photodynamic and immunotherapy

X Meng, Y Han, S Wang, X Wang, Z Zhang, S Yao… - Nano Today, 2023 - Elsevier
For photodynamic therapy (PDT), traditional type II photosensitizers rely on local molecular
oxygen to produce highly cytotoxic singlet oxygen (1 O 2) to kill tumor cells, which is …

Spin–Orbit Charge‐Transfer Intersystem Crossing (ISC) in Compact Electron Donor–Acceptor Dyads: ISC Mechanism and Application as Novel and Potent …

Z Wang, M Ivanov, Y Gao, L Bussotti… - … A European Journal, 2020 - Wiley Online Library
Spin–orbit charge‐transfer intersystem crossing (SOCT‐ISC) is useful for the preparation of
heavy atom‐free triplet photosensitisers (PSs). Herein, a series of perylene‐Bodipy compact …