[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

Neuropharmacological effects of the main phytocannabinoids: a narrative review

RG Dos Santos, JEC Hallak, JAS Crippa - … and neuropsychiatric disorders, 2021 - Springer
Cannabis can synthetize more than 400 compounds, including terpenes, flavonoids, and
more than 100 phytocannabinoids. The main phytocannabinoids are Δ-9 …

[HTML][HTML] Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy …

CM Pretzsch, J Freyberg, B Voinescu… - …, 2019 - nature.com
There is increasing interest in the use of cannabis and its major non-intoxicating component
cannabidiol (CBD) as a treatment for mental health and neurodevelopmental disorders …

Deconstructing the neurobiology of cannabis use disorder

JMN Ferland, YL Hurd - Nature Neuroscience, 2020 - nature.com
There have been dramatic changes worldwide in the attitudes toward and consumption of
recreational and medical cannabis. Cannabinoid receptors, which mediate the actions of …

Cannabinoid treatments for anxiety: A systematic review and consideration of the impact of sleep disturbance

AJ Narayan, LA Downey, B Manning… - … & Biobehavioral Reviews, 2022 - Elsevier
Cannabidiol's (CBD) safety profile and broad action has made it a popular treatment option
for anxiety and co-occurring sleep disturbance. However, its efficacy in healthy and clinical …

The effect of cannabidiol (CBD) on low-frequency activity and functional connectivity in the brain of adults with and without autism spectrum disorder (ASD)

CM Pretzsch, B Voinescu, MA Mendez… - Journal of …, 2019 - journals.sagepub.com
Background: The potential benefits of cannabis and its major non-intoxicating component
cannabidiol (CBD) are attracting attention, including as a potential treatment in …

[HTML][HTML] The impact of cannabidiol on human brain function: a systematic review

A Batalla, J Bos, A Postma, MG Bossong - Frontiers in pharmacology, 2021 - frontiersin.org
Background: Accumulating evidence suggests that the non-intoxicating cannabinoid
compound cannabidiol (CBD) may have antipsychotic and anxiolytic properties, and thus …

Dissociable effects of cannabis with and without cannabidiol on the human brain's resting-state functional connectivity

MB Wall, R Pope, TP Freeman… - Journal of …, 2019 - journals.sagepub.com
Background: Two major constituents of cannabis are Δ9-tetrahydrocannabinol (THC) and
cannabidiol (CBD). THC is the main psychoactive component; CBD may buffer the user …

The Yin and Yang of Cannabis: a systematic review of human neuroimaging evidence of the differential effects of Δ9-tetrahydrocannabinol and cannabidiol

B Gunasekera, C Davies, R Martin-Santos… - Biological Psychiatry …, 2021 - Elsevier
Abstract Cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC) have been the most
investigated cannabinoids at the human and preclinical levels, although the neurobiological …

Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool

CMB Kwee, JMA van Gerven… - Journal of …, 2022 - journals.sagepub.com
Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic
potential in pathological anxiety. Dosing guidelines to inform future human studies are …