Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

To determine whether graft-versus-leukemia (GVL) reactions are important in preventing
leukemia recurrence after bone marrow transplantation, we studied 2,254 persons receiving …

ATURAL KILLER (NK) cells comprise 10% to 15% N of human peripheral blood
lymphocytes (PBL) and most have the morphology of large granular lymphocytes (LGL).'s2 …

To assess the influence of graft-versus-host disease (GVHD) on recurrent leukemia and
survival after allogeneic marrow transplantation, we studied 1,202 patients with acute …

Infection is the leading cause of non-relapse mortality after allogeneic haematopoietic cell
transplantation (HCT). This occurs as a result of dysfunction to the host immune system from …

Peripheral blood stem cells (PBSCs) have been used rarely for allogeneic transplantation
because of concerns regarding graft failure and graft-versus-host disease (GVHD). We …

Donor lymphocyte infusions can reinduce complete remission in the majority of patients with
chronic myelogenous leukemia (CML) who relapse into chronic phase after allogeneic bone …

Allogeneic stem cell transplantation has continued to evolve as a common procedure for the
treatment of hematological malignancies and bone marrow failure. Donor bone marrow and …

Natural killer (NK) cells represent a subset of lymphocytes (up to 15%), distinguishable from
T and B lymphocytes by their morphology, phenotype, and functional capability to …