Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction

A Colson, P Sonveaux, F Debiève… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

[HTML][HTML] Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health

T Feng, Y Liu - Computational and structural biotechnology journal, 2022 - Elsevier
The presence of microbial communities in the reproductive tract has been revealed, and this
resident microbiota is involved in the maintenance of health. Intentional modulation via …

[HTML][HTML] Temporal trends in microplastic accumulation in placentas from pregnancies in Hawaiʻi

RB Weingrill, MJ Lee, P Benny, J Riel, K Saiki… - Environment …, 2023 - Elsevier
Microplastics are created for commercial use, are shed from textiles, or result from the
breakdown of larger plastic items. Recent reports have shown that microplastics accumulate …

Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases

S Tung, E Delavogia, A Fernandez-Gonzalez… - Seminars in …, 2023 - Elsevier
Preterm birth and intrapartum related complications account for a substantial amount of
mortality and morbidity in the neonatal period despite significant advancements in neonatal …

[PDF][PDF] Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction

R Spencer, K Maksym, K Hecher… - Journal of Clinical …, 2023 - Am Soc Clin Investig
BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal
and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the …

Evolutionary divergence of embryo implantation in primates

D Siriwardena, TE Boroviak - … Transactions of the …, 2022 - royalsocietypublishing.org
Implantation of the conceptus into the uterus is absolutely essential for successful embryo
development. In humans, our understanding of this process has remained rudimentary …

Highlighting the trajectory from intrauterine growth restriction to future obesity

KV Gantenbein, C Kanaka-Gantenbein - Frontiers in endocrinology, 2022 - frontiersin.org
During the last decades several lines of evidence reported the association of an adverse
intrauterine environment, leading to intrauterine restriction, with future disease, such as …

Hypoxia and oxidative stress induce sterile placental inflammation in vitro

BC Baker, AEP Heazell, C Sibley, R Wright, H Bischof… - Scientific reports, 2021 - nature.com
Fetal growth restriction (FGR) and stillbirth are associated with placental dysfunction and
inflammation and hypoxia, oxidative and nitrative stress are implicated in placental damage …

Fetal growth restriction and stillbirth: Biomarkers for identifying at risk fetuses

VJ King, L Bennet, PR Stone, A Clark, AJ Gunn… - Frontiers in …, 2022 - frontiersin.org
Fetal growth restriction (FGR) is a major cause of stillbirth, prematurity and impaired
neurodevelopment. Its etiology is multifactorial, but many cases are related to impaired …

Rational design of nanomedicine for placental disorders: birthing a new era in women's reproductive health

HC Geisler, HC Safford, MJ Mitchell - Small, 2024 - Wiley Online Library
The placenta is a transient organ that forms during pregnancy and acts as a biological
barrier, mediating exchange between maternal and fetal circulation. Placental disorders …