Biologically active isoquinoline alkaloids covering 2014–2018

XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

E Plazas, DR Muñoz - Pharmacological Research, 2022 - Elsevier
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

[HTML][HTML] MiR-31 mediates inflammatory signaling to promote re-epithelialization during skin wound healing

J Shi, X Ma, Y Su, Y Song, Y Tian, S Yuan… - Journal of Investigative …, 2018 - Elsevier
Wound healing is essential for skin repair after injury, and it consists of hemostasis,
inflammation, re-epithelialization, and remodeling phases. Successful re-epithelialization …

A critical review: traditional uses, phytochemistry, pharmacology and toxicology of Stephania tetrandra S. Moore (Fen Fang Ji)

Y Jiang, M Liu, H Liu, S Liu - Phytochemistry Reviews, 2020 - Springer
Abstract Stephania tetrandra S. Moore (S. tetrandra) is distributed widely in tropical and
subtropical regions of Asia and Africa. The root of this plant is known in Chinese as “Fen …

NF-κB and its crosstalk with endoplasmic reticulum stress in atherosclerosis

W Li, K Jin, J Luo, W Xu, Y Wu, J Zhou… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis (AS) is a common cardiovascular disease with complex pathogenesis, in
which multiple pathways and their interweaving regulatory mechanism remain unclear. The …

[HTML][HTML] Ultrasound-assisted extraction, optimization, and purification of total flavonoids from Daphnegenkwa and analysis of their antioxidant, anti-inflammatory, and …

Y Xiang, Z Liu, Y Liu, B Dong, C Yang, H Li - Ultrasonics Sonochemistry, 2024 - Elsevier
Daphne genkwa (D. genkwa) is the dried flower buds of a Chinese medicinal plant with
multiple biological activities. Response surface methodology (RSM) combined with artificial …

Engineered production of bioactive natural products from medicinal plants

O Fidan, J Ren, J Zhan - World Journal of Traditional Chinese …, 2022 - journals.lww.com
Plant natural products have been particularly important due to their use in food, cosmetic,
and pharmaceutical industries. In particular, Traditional Chinese Medicine provides a …

Bioprospecting-based untargeted metabolomics identifies alkaloids as potential anti-inflammatory bioactive markers of Ocotea species (Lauraceae)

A Katchborian-Neto, K de Jesus Nicácio, JC Cruz… - Phytomedicine, 2023 - Elsevier
Abstract Background Species within the Ocotea genus (Lauraceae), have demonstrated an
interesting profile of bioactivities. Renowned for their diverse morphology and intricate …

Integrative open workflow for confident annotation and molecular networking of metabolomics MSE/DIA data

A Katchborian-Neto, MF Alves… - Briefings in …, 2024 - academic.oup.com
Liquid chromatography coupled with high-resolution mass spectrometry data-independent
acquisition (LC-HRMS/DIA), including MSE, enable comprehensive metabolomics analyses …