The role of long non-coding RNAs in intracranial aneurysms and subarachnoid hemorrhage

I Gareev, O Beylerli, G Aliev, V Pavlov, A Izmailov… - Life, 2020 - mdpi.com
Intracranial aneurysms (IAs) represent the most complex and relevant problem of modern
neurology and neurosurgery. They serve as one of the main causes of non-traumatic …

Non-coding RNAs role in intracranial aneurysm: general principles with focus on inflammation

R Rikhtegar, PJ Mosimann, J Rothaupt… - Life sciences, 2021 - Elsevier
Intracranial aneurysm (IA) is one of the most challenging vascular lesions in the brain for
clinicians. It was reported that 1%–6% of the world's population is affected by IAs. Owing to …

LncRNA ANRIL Facilitates Vascular Smooth Muscle Cell Proliferation and Suppresses Apoptosis via Modulation of miR-7/FGF2 Pathway in Intracranial Aneurysms

Y Hu, W Chen, C Li, X Wang, J Luo, B Cheng - Neurocritical Care, 2022 - Springer
Background Proliferation and apoptosis of vascular smooth muscle cells (VSMCs) are linked
to intracranial aneurysm (IA) formation and progression. Long antisense noncoding RNA in …

Circular RNA expression profile in human primary multiple intracranial aneurysm

H Cao, J Chen, X Lai, T Liu, P Qiu… - Experimental and …, 2021 - spandidos-publications.com
Primary multiple intracranial aneurysm (MIA) is a vascular disease that frequently leads to
fatal vascular rupture and subarachnoid hemorrhage. However, the epigenetic regulation …

Characterization of long non-coding RNA signatures of intracranial aneurysm in circulating whole blood

VM Tutino, KE Poppenberg, RJ Damiano… - Molecular Diagnosis & …, 2020 - Springer
Abstract Background and Objective Long non-coding RNAs (lncRNAs) may serve as
biomarkers for complex disease states, such as intracranial aneurysms. In this study, we …

The Role of Epigenetics in Brain Aneurysm and Subarachnoid Hemorrhage: A Comprehensive Review

I Fernández-Pérez, A Macias-Gómez… - International Journal of …, 2024 - mdpi.com
This comprehensive review explores the emerging field of epigenetics in intracranial
aneurysm (IA) and aneurysmal subarachnoid hemorrhage (aSAH). Despite recent …

Exploring the association of long noncoding RNA expression profiles with intracranial aneurysms, based on sequencing and related bioinformatics analysis

Y Sun, Y Wen, Q Ruan, L Yang, S Huang, X Xu… - BMC medical …, 2020 - Springer
Background The present study aims to investigate the complete long non-coding RNA
(lncRNA) and messenger RNA (mRNA) expression profiles in Intracranial aneurysm (IA) …

Transcriptomic studies on intracranial aneurysms

R Morga, J Pera - Genes, 2023 - mdpi.com
Intracranial aneurysm (IA) is a relatively common vascular malformation of an intracranial
artery. In most cases, its presence is asymptomatic, but IA rupture causing subarachnoid …

Non-coding RNAs as circulating biomarkers for the diagnosis of intracranial aneurysm: A systematic review and meta-analysis

Y Wu, J Zheng, Y Sun, X Wang, H Zhao, F Qiu… - Journal of Stroke and …, 2021 - Elsevier
Background Early diagnosis of intracranial aneurysm (IA) is arduous in the current situation,
and no biomarker is available for the screening of IA. We here systematically evaluate the …

Long non-coding RNA NORAD induces phenotypic regulation of vascular smooth muscle cells through regulating microRNA-136-5p-targeted KDM1A

C Lv, J Wang, S Dai, Y Chen, X Jiang, X Li - Cell Cycle, 2021 - Taylor & Francis
Objective Effect of long non-coding RNAs (lncRNAs) on intracranial aneurysm (IA)
development has been identified, while the role of noncoding RNA activated by DNA …