[HTML][HTML] Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy

YK Mahmoud, HMA Abdelrazek - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Recently, there is growing interest in the natural bioactive components having anticancer
activity. Thymoquinone (TQ), the principle active constituent of black seed (Nigella sativa) …

[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects

A Ahmad, RK Mishra, A Vyawahare, A Kumar… - Saudi Pharmaceutical …, 2019 - Elsevier
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …

Molecular mechanisms of thymoquinone as anticancer agent

F Alhmied, A Alammar, B Alsultan… - … Chemistry & High …, 2021 - ingentaconnect.com
Thymoquinone (TQ), the bioactive constituent of Nigella Sativa seeds, is a well-known
natural compound for the management of several types of cancers. The anti-cancer …

Therapeutic potential of thymoquinone in triple-negative breast cancer prevention and progression through the modulation of the tumor microenvironment

GM Adinew, E Taka, B Mochona, RB Badisa… - Nutrients, 2021 - mdpi.com
To date, the tumor microenvironment (TME) has gained considerable attention in various
areas of cancer research due to its role in driving a loss of immune surveillance and …

Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells

S Haiaty, MR Rashidi, M Akbarzadeh… - … Medicine and Therapies, 2021 - Springer
Background Vasculogenic mimicry (VM) is characterized by the formation of tubular structure
inside the tumor stroma. It has been shown that a small fraction of cancer cells, namely …

Zebrafish models for the evaluation of essential oils (EOs): A comprehensive review

L Wang, M Yu, S Ding, J Cao, X Meng, L Li… - Quality Assurance and …, 2023 - qascf.com
Essential oils (EOs) derived from crops, especially aromatic plants, have been well-
acknowledged to provide several health benefits for humans. Zebrafish as an …

Antioxidant and Antiangiogenic Properties of Phenolic Extract from Pleurotus tuber-regium

S Lin, TC Lai, L Chen, H Kwok, CB Lau… - Journal of Agricultural …, 2014 - ACS Publications
Pleurotus tuber-regium (Fries) Singer (PTR), both an edible and a medicinal mushroom also
known as tiger milk mushroom, has experienced growing popularity and economic …

Thymoquinone effects on cell viability, apoptosis and VEGF-A gene expression level in AGS (CRL-1739) cell line

M Rashid, F Sanjarin, F Sabouni - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: Cancer is one of the most fatal diseases across the world and it was reported
that 90% of cancer fatality depends on its angiogenesis potential. Black seed or Nigella …

Thymoquinone inhibits the migration of mouse neuroblastoma (Neuro-2a) cells by down-regulating MMP-2 and MMP-9

P Arumugam, R Subramanian, JV Priyadharsini… - Chinese journal of …, 2016 - Elsevier
Thymoquinone (TQ), an active component derived from the medial plant Nigella sativa, has
been used for medical purposes for more than 2 000 years. Recent studies have reported …

Role of berberine on angiogenesis and blood flow hemodynamics using zebrafish model

J Nathan, R Shameera, N Devarajan… - Journal of Applied …, 2024 - Wiley Online Library
Angiogenesis and hemodynamic instability created by the irregular blood vessels causes
hypoperfusion and angiogenesis‐mediated diseases. Therefore, therapies focusing on …