Calprotectin in inflammatory bowel disease

F Khaki-Khatibi, D Qujeq, M Kashifard, S Moein… - Clinica chimica acta, 2020 - Elsevier
The term IBD is usually used for referring to a group of inflammatory gastro-intestinal
diseases (mainly Crohn's disease and ulcerative colitis). Accordingly, IBD arises as a result …

Biomarkers of inflammation in inflammatory bowel disease: how long before abandoning single-marker approaches?

G Dragoni, T Innocenti, A Galli - Digestive Diseases, 2021 - karger.com
Background: Inflammatory bowel disease (IBD) is a chronically relapsing disease with a
continuous need for proactive monitoring to decide appropriate treatments and follow-up …

A specific calprotectin neo-epitope [CPa9-HNE] in serum from inflammatory bowel disease patients is associated with neutrophil activity and endoscopic severity

JH Mortensen, D Sinkeviciute… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Endoscopy and the use of faecal calprotectin [faecal CP] are
among the least-favoured methods for assessing disease activity by inflammatory bowel …

[HTML][HTML] Advancing the precision management of inflammatory bowel disease in the era of omics approaches and new technology

XY Liu, H Tang, QY Zhou, YL Zeng… - World Journal of …, 2023 - ncbi.nlm.nih.gov
There is great heterogeneity among inflammatory bowel disease (IBD) patients in terms of
pathogenesis, clinical manifestation, response to treatment, and prognosis, which requires …

Immunopathology and biology-based treatment of steroid-refractory graft-versus-host disease

T Toubai, J Magenau - Blood, The Journal of the American …, 2020 - ashpublications.org
Acute graft-versus-host disease (GVHD) is 1 of the major life-threating complications after
allogeneic cell transplantation. Although steroids remain first-line treatment, roughly one-half …

Elevated fecal and serum calprotectin in COVID-19 are not consistent with gastrointestinal symptoms

H Shokri-Afra, A Alikhani, B Moradipoodeh… - Scientific reports, 2021 - nature.com
Intestinal epithelial cell damage caused by SARS-CoV-2 infection was thought to be
associated with gastrointestinal symptoms and decreased fecal consistency. The …

Lipocalin-2, S100A8/A9, and cystatin C: potential predictive biomarkers of cardiovascular complications in COVID-19

A Gupta, AO Al-Tamimi, R Halwani… - Experimental …, 2022 - journals.sagepub.com
Severe coronavirus (SARS-COV-2) infection often leads to systemic inflammation
accompanied by cardiovascular complications including venous thromboembolism (VTE) …

Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach

E Stemmer, T Zahavi, M Kellerman… - Frontiers in …, 2024 - frontiersin.org
Background Understanding the molecular pathogenesis of inflammatory bowel disease
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …

The value of calprotectin in synovial fluid for the diagnosis of chronic prosthetic joint infection

Z Zhang, Y Cai, G Bai, C Zhang, W Li… - Bone & joint …, 2020 - boneandjoint.org.uk
Aims This study aimed to evaluate calprotectin in synovial fluid for diagnosing chronic
prosthetic joint infection (PJI). Methods A total of 63 patients who were suspected of PJI were …

Circulating levels of calprotectin, a signature of neutrophil activation in prediction of severe respiratory failure in COVID-19 patients: a multicenter, prospective study …

L Garcia de Guadiana-Romualdo… - Inflammation …, 2022 - Springer
Objective Severe COVID-19 is characterized by a dysregulated immune response in which
neutrophils play a critical role. Calprotectin reflects neutrophil activation and is involved in …