Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Nutrigenomics effects have an important role in the manipulation of dietary components for
human benefit, particularly in cancer prevention or treatment. The impact of dietary …

Phytochemicals are natural compounds synthesized as secondary metabolites in plants,
representing an important source of molecules with a wide range of therapeutic applications …

Estrogen receptor (ER)-positive breast cancer, including luminal-A and-B, is the most
common type of breast cancer. Extended exposure to estrogen is associated with an …

Background Green tea is produced from the tea plant Camellia sinensis without
fermentation, and contains characteristic constituents, which are associated with health …

Simple Summary Breast cancers that express estrogen receptor alpha (ER+) are the most
common subtype of breast cancers. Although surgery and anti-estrogen therapies are …

The expression of HOXB2, a homeobox transcription factor, is altered in a variety of solid
tumors. Using an in vivo screen to identify regulators of breast tumor growth in murine …

Background RUNX1T1 is extensively studied in the context of AML1-RUNX1T1 fusion
protein in acute myeloid leukemia. Little is known about the function of RUNX1T1 itself …

The involvement of estrogen in breast tumorigenesis is well established. However, its role in
extracellular matrix (ECM) remodeling, which is crucial to invasion and metastasis of breast …