B Winner, J Winkler - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Adult neurogenesis is limited to specific brain regions in the mammalian brain, such as the hippocampal dentate gyrus and the subventricular zone/olfactory bulb system. Alterations in …
Behavioural, cellular and molecular studies have revealed significant effects of enriched environments on rodents and other species, and provided new insights into mechanisms of …
H Van Praag - Neuromolecular medicine, 2008 - Springer
Research in humans and animals has shown that exercise improves mood and cognition. Physical activity also causes a robust increase in neurogenesis in the dentate gyrus of the …
B Winner, Z Kohl, FH Gage - European Journal of Neuroscience, 2011 - Wiley Online Library
The generation and cell death of newly generated cells have critical roles in brain development and maintenance in the embryonic and adult brain. Alterations in these …
AJ Hannan - Neuropathology and applied neurobiology, 2014 - Wiley Online Library
Environmental enrichment (EE) increases levels of novelty and complexity, inducing enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …
C Zuccato, E Cattaneo - Progress in neurobiology, 2007 - Elsevier
Neurotrophic factors are essential contributors to the survival of peripheral and central nervous system (CNS) neurons, and demonstration of their reduced availability in diseased …
L Menalled, BF El-Khodor, M Patry… - Neurobiology of …, 2009 - Elsevier
Huntington's disease (HD) is one of the few neurodegenerative diseases with a known genetic cause, knowledge that has enabled the creation of animal models using genetic …
Environmental stimulation throughout development adjusts the neurobehavioral systems involved in learning, memory and defensive responses. Environment-mediated phenotypic …
E Bruel-Jungerman, C Rampon… - Reviews in the …, 2007 - degruyter.com
The demonstration that progenitor cells in regions of the adult mammalian brain such as the dentate gyrus of the hippocampus can undergo mitosis and generate new cells that …