Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Elastic fibers are essential constituents of the extracellular matrix of higher vertebrates and
endow several tissues and organs including lungs, skin and blood vessels with elasticity …

As the primary component of elastic fibers, elastin plays an important role in maintaining the
elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and …

Elastin is an important protein of the extracellular matrix of higher vertebrates, which confers
elasticity and resilience to various tissues and organs including lungs, skin, large blood …

Aortic dimensions and distensibility are key risk factors for aortic aneurysms and dissections,
as well as for other cardiovascular and cerebrovascular diseases. We present genome-wide …

Elastic fibers are extracellular components of higher vertebrates and confer elasticity and
resilience to numerous tissues and organs such as large blood vessels, lungs, and skin …

Extracellular matrix (ECM) provides both structural support and dynamic microenvironment
for cells regulating their behavior and fate. As a critical component of stem cell niche ECM …

Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-
containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation …

Once considered as inert, the extracellular matrix recently revealed to be biologically active.
Elastin is one of the most important components of the extracellular matrix. Many vital organs …

The incidence of cardiovascular diseases is increasing worldwide with the growing aging of
the population. Biological aging has major influence on the vascular tree and is associated …