Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex
Recent advances in multi-electrode array technology have made it possible to monitor large
neuronal ensembles at cellular resolution in animal models. In humans, however, current …
neuronal ensembles at cellular resolution in animal models. In humans, however, current …
Long-term ecological assessment of intracranial electrophysiology synchronized to behavioral markers in obsessive-compulsive disorder
Detection of neural signatures related to pathological behavioral states could enable
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …
[HTML][HTML] Deep brain stimulation for depression informed by intracranial recordings
The success of deep brain stimulation (DBS) for treating Parkinson's disease has led to its
application to several other disorders, including treatment-resistant depression. Results with …
application to several other disorders, including treatment-resistant depression. Results with …
[HTML][HTML] Spatial fidelity of MEG/EEG source estimates: A general evaluation approach
Low spatial resolution is often cited as the most critical limitation of magneto-and
electroencephalography (MEG and EEG), but a unifying framework for quantifying the …
electroencephalography (MEG and EEG), but a unifying framework for quantifying the …
Modular pipeline for reconstruction and localization of implanted intracranial ECoG and sEEG electrodes
Implantation of electrodes in the brain has been used as a clinical tool for decades to
stimulate and record brain activity. As this method increasingly becomes the standard of …
stimulate and record brain activity. As this method increasingly becomes the standard of …
Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
[HTML][HTML] Decoding depression severity from intracranial neural activity
Background Disorders of mood and cognition are prevalent, disabling, and notoriously
difficult to treat. Fueling this challenge in treatment is a significant gap in our understanding …
difficult to treat. Fueling this challenge in treatment is a significant gap in our understanding …
[HTML][HTML] Imaging versus electrographic connectivity in human mood-related fronto-temporal networks
Background The efficacy of psychiatric DBS is thought to be driven by the connectivity of
stimulation targets with mood-relevant fronto-temporal networks, which is typically evaluated …
stimulation targets with mood-relevant fronto-temporal networks, which is typically evaluated …
Theta-burst direct electrical stimulation remodels human brain networks
Abstract Theta-burst stimulation (TBS), a patterned brain stimulation technique that mimics
rhythmic bursts of 3–8 Hz endogenous brain rhythms, has emerged as a promising …
rhythmic bursts of 3–8 Hz endogenous brain rhythms, has emerged as a promising …
Case report of dual-site neurostimulation and chronic recording of cortico-striatal circuitry in a patient with treatment refractory obsessive compulsive disorder
ST Olsen, I Basu, MT Bilge, A Kanabar… - Frontiers in Human …, 2020 - frontiersin.org
Psychiatric disorders are increasingly understood as dysfunctions of hyper-or
hypoconnectivity in distributed brain circuits. A prototypical example is obsessive …
hypoconnectivity in distributed brain circuits. A prototypical example is obsessive …