Effects of seawater temperature and acute Vibrio sp. challenge on the haemolymph immune and metabolic responses of adult mussels (Perna canaliculus)

JA Ericson, L Venter, MRV Welford, K Kumanan… - Fish & Shellfish …, 2022 - Elsevier
Abstract The New Zealand Greenshell™ mussel (Perna canaliculus) is an endemic bivalve
species with cultural importance, that is harvested recreationally and commercially …

Molecular dynamics simulation studies on uptake of fipronil sulfone by gut microbiome and its influence on risk for cause of Parkinson's disease

A Bhat, V Chandramohan, S Sabat - Molecular Simulation, 2024 - Taylor & Francis
Biotransformation of Fipronil forms three metabolites: fipronil sulfone, fipronil sulfide and
fipronil desulfinyl. Among the triad of metabolites, fipronil sulfone exhibits quantitatively …

Comparative Proteome-wide Characterization of Three Different Tissues of High-Protein Mutant and Wild Type Unravels Protein Accumulation Mechanisms in Rice …

CW Min, R Gupta, JY Jung, R Rakwal… - Journal of Agricultural …, 2023 - ACS Publications
Improving the proteins and amino acid contents of rice seeds is one of the prime objectives
of plant breeders. We recently developed an EMS mutant/high-protein mutant (HPM) of rice …

L, L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds

AJ Triassi, MS Wheatley, MA Savka, HM Gan… - Frontiers in …, 2014 - frontiersin.org
Despite the urgent need for sustained development of novel antibacterial compounds to
combat the drastic rise in antibiotic resistant and emerging bacterial infections, only a few …

Synonymous codon bias and functional constraint on GC3-related DNA backbone dynamics in the prokaryotic nucleoid

GA Babbitt, MA Alawad, KV Schulze… - Nucleic acids …, 2014 - academic.oup.com
While mRNA stability has been demonstrated to control rates of translation, generating both
global and local synonymous codon biases in many unicellular organisms, this explanation …

Biochemical characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2, 6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM …

SE McGroty, DT Pattaniyil, D Patin, D Blanot… - PLoS …, 2013 - journals.plos.org
Verrucomicrobium spinosum is a Gram-negative bacterium that is related to bacteria from
the genus Chlamydia. The bacterium is pathogenic towards Drosophila melanogaster and …

Structure–function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

JM Crowther, PJ Cross, MR Oliver, MM Leeman… - Journal of Biological …, 2019 - ASBMB
meso-Diaminopimelate decarboxylase catalyzes the decarboxylation of meso-
diaminopimelate, the final reaction in the diaminopimelate l-lysine biosynthetic pathway. It is …

[HTML][HTML] Differential response of orthologous L, L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds

SMK McKinnie, EM Rodriguez-Lopez… - Bioorganic & Medicinal …, 2014 - Elsevier
Abstract l, l-Diaminopimelate aminotransferase (DapL) is an enzyme required for the
biosynthesis of meso-diaminopimelate (m-DAP) and l-lysine (Lys) in some bacteria and …

Identification and partial characterization of a novel UDP-N-acetylenolpyruvoylglucosamine reductase/UDP-N-acetylmuramate: L-alanine ligase fusion enzyme from …

KF Naqvi, D Patin, MS Wheatley, MA Savka… - Frontiers in …, 2016 - frontiersin.org
The enzymes involved in synthesizing the bacterial cell wall are attractive targets for the
design of antibacterial compounds, since this pathway is essential for bacteria and is absent …

The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution

AR Cala, MT Nadeau, J Abendroth… - … Section F: Structural …, 2016 - journals.iucr.org
In bacteria, the second committed step in the diaminopimelate/lysine anabolic pathways is
catalyzed by the enzyme dihydrodipicolinate reductase (DapB). DapB catalyzes the …