The role of non-diagnostic features in the pathophysiology of autism spectrum disorders
(ASDs) is unclear. Increasing evidence suggests immune system alterations in ASD may be …

Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …

Objective There has been rapid growth in research regarding inflammation in
neuropsychiatric disorders as it relates to youth. We therefore set out to systematically …

Background: Although increasing evidence suggests an association between alterations in
peripheral cytokines and autism spectrum disorder (ASD), a consensus is lacking. To …

Autism spectrum disorder (ASD) involves a complex interplay of both genetic and
environmental risk factors, with immune alterations and synaptic connection deficiency in …

Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …

Objectives The neurobiological basis for autism remains poorly understood. However,
research suggests that environmentalfactors and neuroinflammation, as well as genetic …

The increasing incidence of autism suggests a major environmental influence. Epidemiology
has implicated many candidates and genetics many susceptibility genes. Gene/environment …

Nitric oxide (NO) is a gaseous transmitter produced by nitric oxide synthases (NOSs). The
neuronal isoform (NOS‐I, encoded by NOS1) is the main source of NO in the central nervous …

Background In the search for the causes of autism spectrum disorders (ASD), inflammatory
markers have emerged as potential candidates. The present meta-analysis was performed …