Background: Traumatic brain injury (TBI) constitutes the primary reason for mortality and
morbidity in persons worldwide below 45 years of age. 1.7 million Traumatic events occur …

The knowledge of the pathophysiology after traumatic head injury is necessary for adequate
and patient-oriented treatment. As the primary insult, which represents the direct mechanical …

Microdialysis enables the chemistry of the extracellular interstitial space to be monitored.
Use of this technique in patients with acute brain injury has increased our understanding of …

Object Cerebral ischemia is the leading cause of preventable death in cases of major
trauma with severe traumatic brain injury (TBI). Intracranial pressure (ICP) control and …

Background In COVID-19 patients with acute respiratory distress syndrome (ARDS), the
effectiveness of ventilatory rescue strategies remains uncertain, with controversial efficacy …

Objective: In this study, available medical literature were reviewed to determine whether
brain hypoxia as measured by brain tissue oxygen (Bto 2) levels is associated with …

BACKGROUND: Brain hypoxia (BH) can aggravate outcome after severe traumatic brain
injury (TBI). Whether BH or reduced brain oxygen (Pbto 2) is an independent outcome …

Observational clinical studies demonstrate that brain hypoxia is associated with poor
outcome after severe traumatic brain injury (TBI). In this study, available medical literature …

Background and Purpose—To identify a minimally acceptable cerebral perfusion pressure
threshold above which the risks of brain tissue hypoxia (BTH) and oxidative metabolic crisis …

Introduction There is a substantial amount of evidence from animal models that early brain
injury (EBI) may play an important role for secondary brain injury after aneurysmal …