Novel prognostic clinical factors and biomarkers for outcome prediction in head and neck cancer: a systematic review

V Budach, I Tinhofer - The Lancet Oncology, 2019 - thelancet.com
Current algorithms for the clinical management of patients with squamous cell carcinoma of
the head and neck (HNSCC) are based on a stage-dependent strategy where all patients at …

Molecular insights into oral malignancy

A Deshmukh, KN Rao, RD Arora, NM Nagarkar… - Indian journal of surgical …, 2022 - Springer
Squamous cell carcinoma constitutes around 95% of malignancies in the oral cavity. The 5-
year overall survival has not substantially improved for oral cancers over the last few …

Recurrent copy number alterations involving EGFR, CDKN2A, and CCND1 in oral premalignant lesions

F Jäwert, A Fehr, J Öhman, G Stenman… - Journal of Oral …, 2022 - Wiley Online Library
Background A major challenge in the management of patients with oral leukoplakia is the
difficulty to identify patients at high risk of developing oral squamous cell carcinoma. Our …

Gold nanorods reflectance discriminate benign from malignant oral lesions

A Hirshberg, I Allon, I Novikov, R Ankri… - … , Biology and Medicine, 2017 - Elsevier
Nanoparticle-based contrast agents have been used as an imaging tool for selectively
detecting cancerous processes. We aimed to evaluate the detection sensitivity of reflection …

The role of SPP1 as a prognostic biomarker and therapeutic target in head and neck squamous cell carcinoma

X Cai, H Zhang, T Li - International Journal of Oral and Maxillofacial …, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is one of the most common
malignancies and has a low 5-year survival rate. Mounting evidence suggests that oral …

Oral carcinogenesis and malignant transformation

CS Farah, K Shearston, AP Nguyen… - Premalignant conditions of …, 2019 - Springer
Cancer of the oral cavity and oropharynx is a significant health burden, with over 300,000
new cases diagnosed annually [1]. Oral squamous cell carcinoma (OSCC) constitutes 95 …

Clinicopathological features of squamous cell carcinoma of the oral cavity and oropharynx in young patients

RCP Martinez, HP Sathasivam, B Cosway… - British Journal of Oral …, 2018 - Elsevier
Our aim was to examine the clinicopathological features of squamous cell carcinoma (SCC)
of the oral cavity and oropharynx in a group of young patients who were dignosed during a …

Gene expression changes associated with malignant transformation of oral potentially malignant disorders

HP Sathasivam, J Casement, T Bates… - Journal of Oral …, 2021 - Wiley Online Library
Background A large number of oral squamous cell carcinomas (OSCCs) are believed to be
preceded by oral potentially malignant disorders (OPMD) that have an increased likelihood …

A disintegrin and metalloproteinase domain 17-epidermal growth factor receptor signaling contributes to oral cancer pain

NN Scheff, Y Ye, ZR Conley, JW Quan, YVR Lam… - Pain, 2020 - journals.lww.com
Cancer cells secrete pronociceptive mediators that sensitize adjacent sensory neurons and
cause pain. Identification and characterization of these mediators could pinpoint novel …

A Systematic Review on a comprehensive evaluation of clinical prognostic variables and new biomarkers for head and neck cancer outcome

VN Sreekumar, M Madhulaxmi, R Ankathil… - Journal of …, 2022 - pnrjournal.com
All patients with the same TNM stage are treated according to the current algorithms for the
clinical treatment of patients with head and neck squamous cell carcinoma (HNSCC) …