Nanomaterials for cancer therapy: current progress and perspectives
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …
Extracellular matrix alterations in metastatic processes
M Paolillo, S Schinelli - International journal of molecular sciences, 2019 - mdpi.com
The extracellular matrix (ECM) is a complex network of extracellular-secreted
macromolecules, such as collagen, enzymes and glycoproteins, whose main functions deal …
macromolecules, such as collagen, enzymes and glycoproteins, whose main functions deal …
[HTML][HTML] Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Bone metastases are devastating complications of cancer. They are particularly common in
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …
Proteogenomics of non-smoking lung cancer in East Asia delineates molecular signatures of pathogenesis and progression
Summary Lung cancer in East Asia is characterized by a high percentage of never-smokers,
early onset and predominant EGFR mutations. To illuminate the molecular phenotype of this …
early onset and predominant EGFR mutations. To illuminate the molecular phenotype of this …
Insights into the role of matrix metalloproteinases in cancer and its various therapeutic aspects: a review
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate the
turnover of extracellular matrix (ECM) components. Gross and La Piere discovered MMPs in …
turnover of extracellular matrix (ECM) components. Gross and La Piere discovered MMPs in …
Soluble programmed cell death ligand 1 as a novel biomarker for nivolumab therapy for non–small-cell lung cancer
Y Okuma, H Wakui, H Utsumi, Y Sagawa, Y Hosomi… - Clinical lung cancer, 2018 - Elsevier
Background Biomarkers for predicting the effect of anti–programmed cell death 1 (PD-1)
monoclonal antibody against non–small-cell lung cancer (NSCLC) are urgently required …
monoclonal antibody against non–small-cell lung cancer (NSCLC) are urgently required …
Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy
Application of nanotechnologies to cancer therapy might increase solubility and/or
bioavailability of bioactive compounds of natural or synthetic origin and offers other potential …
bioavailability of bioactive compounds of natural or synthetic origin and offers other potential …
Myeloid cell–derived PROS1 inhibits tumor metastasis by regulating inflammatory and immune responses via IL-10
A Maimon, V Levi-Yahid, K Ben-Meir… - The Journal of …, 2021 - Am Soc Clin Investig
Stimulation of TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases promotes tumor
progression through numerous cellular mechanisms. TAM cognate ligands GAS6 and …
progression through numerous cellular mechanisms. TAM cognate ligands GAS6 and …
Mechanisms and future of non-small cell lung cancer metastasis
T Zhu, X Bao, M Chen, R Lin, J Zhuyan, T Zhen… - Frontiers in …, 2020 - frontiersin.org
Lung cancer, renowned for its fast progression and metastatic potency, is rising to become a
leading cause of death globally. It has been long observed that lung cancer is particularly …
leading cause of death globally. It has been long observed that lung cancer is particularly …
Acetylcholine signaling system in progression of lung cancers
JR Friedman, SD Richbart, JC Merritt, KC Brown… - Pharmacology & …, 2019 - Elsevier
The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …