The metabolic syndrome is prevalent in developed nations and accounts for the largest
burden of non-communicable diseases worldwide. The metabolic syndrome has direct …

Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

Single-nucleotide polymorphisms (SNPs) in the Toll-like receptor 4 (TLR4) gene have been
documented in type 2 diabetes mellitus (T2DM) and other diseases in the Saudi population …

Although high-fat diet (HFD) has been implicated in the development of colorectal cancer
(CRC), the critical signaling molecule that mediates the cancer growth is not well-defined …

Despite the increasing number of available therapeutic methods, the prognosis of non‑small
cell lung cancer (NSCLC) remains poor. Furthermore, side effects are an important limiting …

Colorectal cancer is the third most incident and second most lethal type of cancer worldwide.
Lifestyle and dietary patterns are the key factors for higher disease development risk. The …

Annona squamosa L. is an important medicinal plant used in traditional medicine for the
treatment of various diseases. Different parts of A. squamosa L. have various therapeutic …

Background Colitis-associated cancer (CAC) is a complication of inflammatory bowel
disease (IBD) with a poor prognosis because it is often diagnosed in advanced stages with …

Background Toll-like receptors (TLRs) play essential role in innate and acquired immunity,
are expressed in various cell types, and are associated with altered susceptibility to many …

Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer
(CRC), with men generally exhibiting a slightly higher incidence than women. Research …