Strategic use of visible-light photoredox catalysis in natural product synthesis

SP Pitre, LE Overman - Chemical Reviews, 2021 - ACS Publications
Recent progress in the development of photocatalytic reactions promoted by visible light is
leading to a renaissance in the use of photochemistry in the construction of structurally …

Cyclopropanation strategies in recent total syntheses

C Ebner, EM Carreira - Chemical reviews, 2017 - ACS Publications
Complex molecular architectures containing cyclopropanes present significant challenges
for any synthetic chemist. This review aims to highlight the strategic considerations for …

Dearomative ring expansion of thiophenes by bicyclobutane insertion

H Wang, H Shao, A Das, S Dutta, HT Chan, C Daniliuc… - Science, 2023 - science.org
Skeletal ring enlargement is gaining renewed interest in synthetic chemistry and has
recently focused on insertion of one or two atoms. Strategies for heterocyclic expansion …

Photoinduced remote functionalisations by iminyl radical promoted C− C and C− H bond cleavage cascades

EM Dauncey, SP Morcillo, JJ Douglas… - Angewandte …, 2018 - Wiley Online Library
A photoinduced cascade strategy leading to a variety of differentially functionalised nitriles
and ketones has been developed. These reactions rely on the oxidative generation of iminyl …

Thirty Years of (TMS)3SiH: A Milestone in Radical-Based Synthetic Chemistry

C Chatgilialoglu, C Ferreri, Y Landais… - Chemical …, 2018 - ACS Publications
This review is an update on tris (trimethylsilyl) silane, TTMSS, in organic chemistry, focusing
on the advancements of the past decade. The overview includes a wide range of chemical …

Intermolecular organophotocatalytic cyclopropanation of unactivated olefins

DM Fischer, H Lindner, WM Amberg… - Journal of the …, 2023 - ACS Publications
Intermolecular cyclopropanation of mono-, di-, and trisubstituted olefins with α-bromo-β-
ketoesters and α-bromomalonates under organophotocatalysis is reported. The reaction …

Ring‐Expansion Reactions in the Synthesis of Macrocycles and Medium‐Sized Rings

JR Donald, WP Unsworth - Chemistry–A European Journal, 2017 - Wiley Online Library
Functionalised macrocycles and medium‐sized rings have applications in a number of
scientific fields, ranging from medicinal chemistry and supramolecular chemistry, to catalysis …

Cascade reactions in total synthesis

KC Nicolaou, DJ Edmonds… - Angewandte Chemie …, 2006 - Wiley Online Library
The design and implementation of cascade reactions is a challenging facet of organic
chemistry, yet one that can impart striking novelty, elegance, and efficiency to synthetic …

Metal-mediated reductive hydrodehalogenation of organic halides

F Alonso, IP Beletskaya, M Yus - Chemical reviews, 2002 - ACS Publications
Organic halides are very important and versatile compounds with many applications as
starting materials, solvents, reagents, and intermediates in synthetic organic chemistry. 1 …

Metal-mediated synthesis of medium-sized rings

L Yet - Chemical reviews, 2000 - ACS Publications
The importance of medium-and large-sized rings in organic chemistry is exemplified by their
being the structural core of a large number of biologically important natural products1 and …