Experimental and thermodynamic investigation of gemifloxacin solubility in supercritical CO2 for the production of nanoparticles

F Arabgol, M Amani, NS Ardestani… - The Journal of Supercritical …, 2024 - Elsevier
The effective use of the supercritical technology in the production of new pharmaceutical
formulations with greater bioavailability requires the determination of the solubility of …

[HTML][HTML] Solubility measurement of Ceftriaxone sodium in SC-CO2 and thermodynamic modeling using PR-KM EoS and vdW mixing rules with semi-empirical models

G Sodeifian, H Bagheri, M Ashjari… - Case Studies in Thermal …, 2024 - Elsevier
The complete investigation of the solubility of Ceftriaxone sodium drug has not yet been
conducted. This communication investigates the solubility of Ceftriaxone sodium drug in …

Investigating the Influence of Cosolvents on the Solubility of Febuxostat in Supercritical CO2: Experimental Analysis and Artificial Intelligence Study

OS Alsawad, AQ Mohammad AlHamad… - Journal of Chemical & …, 2024 - ACS Publications
Assessing the solubility of pharmaceutical compounds in supercritical carbon dioxide
(scCO2) is a fundamental prerequisite for advancing the application of supercritical …

Nanomedicine formulation using green supercritical processing: experimental solubility measurement and theoretical investigation

F Arabgol, M Amani, NS Ardestani… - Chemical Engineering …, 2024 - Wiley Online Library
To develop effective pharmaceutical formulations using supercritical carbon dioxide (scCO2)
techniques, it is necessary to obtain the solubility of the medicinal ingredients in scCO2. In …

[HTML][HTML] Binary and ternary approach of solubility of Rivaroxaban for preparation of developed nano drug using supercritical fluid

M Askarizadeh, N Esfandiari, B Honarvar… - Arabian Journal of …, 2024 - Elsevier
This study addressed the solubility of Rivaroxaban in supercritical carbon dioxide at a
temperature range of 308–338 K and a pressure range of 12–30 MPa with and without a Co …

Simulation and Optimization: A New Direction in Supercritical Technology Based Nanomedicine

Y Huang, Y Zheng, X Lu, Y Zhao, D Zhou, Y Zhang… - Bioengineering, 2023 - mdpi.com
In recent years, nanomedicines prepared using supercritical technology have garnered
widespread research attention due to their inherent attributes, including structural stability …

Comprehensive study of medications solubility in supercritical CO2 with and without co-solvent; Laboratory, theoretical, and intelligent approaches

CY Hsu, DJ Jasim, P Bansal, N Juraev… - Journal of Molecular …, 2024 - Elsevier
Determining the dissolution characteristics of medicines in supercritical CO 2 is vital for
formulating innovative drug delivery systems through an efficient supercritical process. This …

Advancing nanomedicine production via green thermal supercritical processing: Laboratory measurement and thermodynamic modeling

TN Alharby, MM Algahtani, J Alanazi… - Journal of Molecular …, 2023 - Elsevier
Chlorpromazine is an antipsychotic medicine which is used to treat psychotic disorders,
nausea and vomiting. Based on the Biopharmaceutical Classification System (BCS), this …

Mesalazine solubility in supercritical carbon dioxide with and without cosolvent and modeling

SA Sajadian, N Esfandiari, A Rojas, S Hemmati… - Scientific Reports, 2025 - nature.com
In this study, the solubility of mesalazine in supercritical carbon dioxide with and without
cosolvent was carried out for the first time at different temperatures and pressure values …

Assessment of new semi-empirical density based model for prediction the solubility of pharmaceutical components in supercritical carbon dioxide

C Bouhallas, Y Ammi, A Belghait - The Journal of Supercritical Fluids, 2024 - Elsevier
In this paper, a new semi-empirical density-based model was developed to correlate drug
compounds solubility in supercritical carbon dioxide (SC-CO 2) as a function of temperature …