Endogenous and exogenous antioxidants as a tool to ameliorate male infertility induced by reactive oxygen species

T R. Dias, D Martin-Hidalgo, B M. Silva… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Antioxidants are essential for the maintenance of cellular redox
homeodynamics in the male reproductive tract, playing a key role in fertilizing potential …

Protective effects of alpha-lipoic acid, resveratrol, and apigenin against oxidative damages, histopathological changes, and mortality induced by lung irradiation in rats

N Seyedpour, E Motevaseli, S Taeb… - Current …, 2024 - ingentaconnect.com
Aim: This study investigated the protective effects of three antioxidants on radiationinduced
lung injury. Background: Oxidative stress is one of the key outcomes of radiotherapy in …

Alpha-lipoic acid improves sperm motility in infertile men after varicocelectomy: a triple-blind randomized controlled trial

B Abbasi, N Molavi, M Tavalaee, H Abbasi… - Reproductive …, 2020 - Elsevier
Research question Does supplementation with alpha-lipoic acid (ALA) enhance sperm
parameters and/or the status of sperm lipid peroxidation and DNA fragmentation in men who …

Portulaca oleracea seeds' extract alleviates acrylamide-induced testicular dysfunction by promoting oxidative status and steroidogenic pathway in rats

OM Farag, RM Abd-Elsalam, SA El Badawy… - … medicine and therapies, 2021 - Springer
Background Acrylamide (ACR) is a widespread industrial and food contaminant that
garnered considerable attention for its carcinogenic, neurotoxic, and reproductive toxic …

Oxidative stress and endoplasmic reticulum stress are involved in the protective effect of alpha lipoic acid against heat damage in chicken testes

Y Xiong, Q Yin, J Li, S He - Animals, 2020 - mdpi.com
Simple Summary In male animals, heat stress causes injury to the testes, resulting in an
increase in the number of deformed sperm, a reduction in testosterone production, and …

Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction in rats: Crosstalk of NF-ĸB, TGF-β, and PPAR-ϒ pathways

RS Said, HA Mohamed, DH Kassem - Toxicology, 2020 - Elsevier
Radiotherapy is one of the principal approaches employed in the treatment of pelvic
cancers. Nevertheless, testicular dysfunction and infertility are among the most common …

Hypothyroidism: Morphological and metabolic changes in the testis of adult albino rat and the amelioration by alpha-lipoic acid

AA Ibrahim, NA Mohammed, KA Eid… - Folia …, 2021 - journals.viamedica.pl
Background: The objective of this study is to evaluate the influence of carbimazole-induced
hypothyroidism on the testes of adult albino rats and the probable protective effect of alpha …

Alpha-lipoic acid improves the quality of ram spermatozoa stored at 4 C by reducing oxidative stress and increasing mitochondrial potential

X Sun, L Zhang, Y Kang, X Wang, C Jiang… - Frontiers in Veterinary …, 2024 - frontiersin.org
Introduction Ram spermatozoa inevitably produce a large number of reactive oxygen
species (ROS) during liquid storage, leading to oxidative stress and a decline of …

Protective effect of alpha-lipoic acid on di-(2-ethylhexyl) phthalate-induced testicular toxicity in mice

M Goudarzi, M Haghi Karamallah, A Malayeri… - … Science and Pollution …, 2020 - Springer
Phthalates are synthetic chemicals, widely used as plasticizers due to their flexibility in
plastics. Human populations may be exposed to phthalates through direct contact or …

α‐Lipoic acid inhibits testicular and epididymal oxidative damage and improves fertility efficacy in arsenic‐intoxicated rats

P Prathima, R Pavani, S Sukeerthi… - Journal of biochemical …, 2018 - Wiley Online Library
The present study evaluates the protective effect of α‐lipoic acid (LA) against arsenic‐
induced testicular and epididymal oxidative damage in rats. Arsenic caused significant …