Simple Summary Parkinson's disease is a neurodegenerative disorder characterized by the
death of a specific subset of dopamine-producing neurons. This triggers problems with …

Mitochondria are the centers of energy and material metabolism, and they also serve as the
storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function …

WDR45 is an autophagy-related protein that involves in the formation of autophagosome.
Mutations in WDR45 lead to the impairment of autophagy which is associated with the …

An increase in anthropogenic activities results in metal contamination in the ecosystem
which has proven to be a major health risk in humans, as they make entry into cellular …

Simultaneous determination of deferoxamine and vitamin C at the surface of a
nanostructured-modified sensor is reported at this study. The electrode is designed based …

Cytokinins are adenine-based phytohormones that regulate key processes in plants, such
as cell division and differentiation, root and shoot growth, apical dominance, branching, and …

Parkinson's disease (PD) is a challenge because of the ageing of the population and the
disease's complicated pathogenesis. Accumulating evidence showed that iron and …

Abstract Lipocalin-2 (LCN2) is an important regulator of both neuroinflammation and iron
homeostasis. Upregulated LCN2 was observed in reactive astrocytes in the Parkinson's …

Trimethyltin (TMT) is an environmental neurotoxin that mediates dopaminergic neuronal
injury in the brain. In this study, we characterized the toxic mechanism and possible …

Iron is widely linked with the onset and development of Parkinson's disease (PD).
Accumulation of iron induces free radical generation and promotes α-synuclein aggregation …