Vibrational spectroscopy fingerprinting in medicine: from molecular to clinical practice

V Balan, CT Mihai, FD Cojocaru, CM Uritu, G Dodi… - Materials, 2019 - mdpi.com
In the last two decades, Fourier Transform Infrared (FTIR) and Raman spectroscopies turn
out to be valuable tools, capable of providing fingerprint-type information on the composition …

Spectral pre-processing for biomedical vibrational spectroscopy and microspectroscopic imaging

P Lasch - Chemometrics and Intelligent Laboratory Systems, 2012 - Elsevier
Recent years have seen substantial progress toward the application of infrared (IR) and
Raman spectroscopy as useful analytical tools in biomedical research. Vibrational …

Using Fourier transform IR spectroscopy to analyze biological materials

MJ Baker, J Trevisan, P Bassan, R Bhargava… - Nature protocols, 2014 - nature.com
IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …

Distinguishing cell types or populations based on the computational analysis of their infrared spectra

FL Martin, JG Kelly, V Llabjani, PL Martin-Hirsch… - Nature protocols, 2010 - nature.com
Infrared (IR) spectroscopy of intact cells results in a fingerprint of their biochemistry in the
form of an IR spectrum; this has given rise to the new field of biospectroscopy. This protocol …

Infrared spectroscopic imaging: the next generation

R Bhargava - Applied spectroscopy, 2012 - journals.sagepub.com
Infrared (IR) spectroscopic imaging seemingly matured as a technology in the mid-2000s,
with commercially successful instrumentation and reports in numerous applications. Recent …

Extended multiplicative signal correction in vibrational spectroscopy, a tutorial

NK Afseth, A Kohler - Chemometrics and Intelligent Laboratory Systems, 2012 - Elsevier
Extended multiplicative signal correction (EMSC) is a model-based preprocessing technique
that has been frequently used in vibrational spectroscopy. The framework of EMSC allows …

Extracting biological information with computational analysis of Fourier-transform infrared (FTIR) biospectroscopy datasets: current practices to future perspectives

J Trevisan, PP Angelov, PL Carmichael, AD Scott… - Analyst, 2012 - pubs.rsc.org
Applying Fourier-transform infrared (FTIR) spectroscopy (or related technologies such as
Raman spectroscopy) to biological questions (defined as biospectroscopy) is relatively …

Recent applications of quantitative analytical FTIR spectroscopy in pharmaceutical, biomedical, and clinical fields: A brief review

KM Fahelelbom, A Saleh, MMA Al-Tabakha… - Reviews in Analytical …, 2022 - degruyter.com
Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and
implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical …

Analysis of fixed and live single cells using optical photothermal infrared with concomitant Raman spectroscopy

A Spadea, J Denbigh, MJ Lawrence, M Kansiz… - Analytical …, 2021 - ACS Publications
This paper reports the first use of a novel completely optically based photothermal method
(O-PTIR) for obtaining infrared spectra of both fixed and living cells using a quantum …

Emerging themes in image informatics and molecular analysis for digital pathology

R Bhargava, A Madabhushi - Annual review of biomedical …, 2016 - annualreviews.org
Pathology is essential for research in disease and development, as well as for clinical
decision making. For more than 100 years, pathology practice has involved analyzing …