Corticosteroids in ophthalmology: Drug delivery innovations, pharmacology, clinical applications, and future perspectives

SA Gaballa, UB Kompella, O Elgarhy… - Drug Delivery and …, 2021 - Springer
Corticosteroids remain the mainstay of the treatment for various ocular conditions affecting
the ocular surface, anterior and posterior segments of the eye due to their anti-inflammatory …

Cyclodextrin-based ocular drug delivery systems: A comprehensive review

Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

[HTML][HTML] Cyclodextrins and derivatives in drug delivery: New developments, relevant clinical trials, and advanced products

G Kali, S Haddadzadegan, A Bernkop-Schnürch - Carbohydrate Polymers, 2023 - Elsevier
Cyclodextrins (CD) and derivatives are functional excipients that can improve the
bioavailability of numerous drugs. Because of their drug solubility improving properties they …

Advanced formulation approaches for ocular drug delivery: state-of-the-art and recent patents

EB Souto, J Dias-Ferreira, A López-Machado… - Pharmaceutics, 2019 - mdpi.com
The eye presents extensive perspectives and challenges for drug delivery, mainly because
of the extraordinary capacity, intrinsic to this path, for drugs to permeate into the main …

Soft contact lenses as drug delivery systems: a review

I Rykowska, I Nowak, R Nowak - Molecules, 2021 - mdpi.com
This review describes the role of contact lenses as an innovative drug delivery system in
treating eye diseases. Current ophthalmic drug delivery systems are inadequate, particularly …

[HTML][HTML] Cyclodextrins as an encapsulation molecular strategy for volatile organic compounds—Pharmaceutical applications

AC Paiva-Santos, L Ferreira, D Peixoto, F Silva… - Colloids and Surfaces B …, 2022 - Elsevier
The use of essential oils has gained importance due to their wide range of biological
properties. Essential oils comprise a complex mixture of volatile organic compounds (VOCs) …

[HTML][HTML] Lactoferrin-loaded nanostructured lipid carriers (NLCs) as a new formulation for optimized ocular drug delivery

R Varela-Fernández, X García-Otero… - European Journal of …, 2022 - Elsevier
Nanostructured lipid carriers (NLC) are novel lipidic nanosystems that provide significant
improvements in terms of high drug loading capacity and controlled drug release. The …

Hazardous impact of diclofenac on mammalian system: Mitigation strategy through green remediation approach

P Sathishkumar, K Mohan, RAA Meena… - Journal of Hazardous …, 2021 - Elsevier
Diclofenac is an anti-inflammatory drug used as an analgesic. It is often detected in various
environmental sources around the world and is considered as one of the emerging …

Hybrid thermosensitive-mucoadhesive in situ forming gels for enhanced corneal wound healing effect of L-carnosine

Z Fathalla, WW Mustafa, H Abdelkader, H Moharram… - Drug …, 2022 - Taylor & Francis
Purpose Thermosensitive in situ gels have been around for decades but only a few have
been translated into ophthalmic pharmaceuticals. The aim of this study was to combine the …

Microencapsulation for pharmaceutical applications: a review

C Yan, SR Kim - ACS Applied Bio Materials, 2024 - ACS Publications
In order to improve bioavailability, stability, control release, and target delivery of active
pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their …