Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …

Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

INTRODUCTION Fundamental circuit features of the mouse visual system emerge before
the onset of vision, allowing the mouse to perceive objects and detect visual motion …

Optokinetic nystagmus (OKN) assists stabilization of the retinal image during head rotation.
OKN is driven by ON direction selective retinal ganglion cells (ON DSGCs), which encode …

The retina, which processes visual information and sends it to the brain, is an excellent
model for studying neural circuitry. It has been probed extensively ex vivo but has been …

Spontaneous activity refines neural connectivity prior to the onset of sensory experience, but
it remains unclear how such activity instructs axonal connectivity with subcellular precision …

Large numbers of brain regions are active during behaviors. A high-resolution, brain-wide
activity map could identify brain regions involved in specific behaviors. We have developed …

How neuronal computations in the sensory periphery contribute to computations in the
cortex is not well understood. We examined this question in the context of visual-motion …

The diversity of visual input processed by the mammalian visual system requires the
generation of many distinct retinal ganglion cell (RGC) types, each tuned to a particular …

Approaching predators cast expanding shadows (ie, looming) that elicit innate defensive
responses in most animals. Where looming is first detected and how critical parameters of …