Dopamine receptors are widely distributed within the brain where they play critical
modulator roles on motor functions, motivation and drive, as well as cognition. The …

Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …

Economics and mental health are intertwined. Apart from the accumulating evidence of the
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …

Purpose of review: To provide an overview of the underlying neurobiology of tobacco
smoking in schizophrenia, and implications for treatment of this comorbidity. Recent findings …

The past four decades have seen enormous efforts placed on a search for molecular
markers of schizophrenia using positron emission tomography (PET) and single photon …

Dysregulation of striatal dopamine is considered to be an important driver of
pathophysiological processes in schizophrenia. Despite being one of the main origins of …

Dopamine function and reward processing are highly interrelated and involve common brain
regions afferent to the nucleus accumbens, within the mesolimbic pathway. Although …

Auditory verbal hallucinations (AVH) are an important characteristic of schizophrenia.
Repeated transcranial magnetic stimulation (rTMS) has been evidence to be effective in …

Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence,
disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is …

Background A reduced presynaptic dopamine neurotransmission has long been implicated
in major depressive disorder (MDD). However, molecular imaging studies that assessed the …