RFamide-related peptide neurons modulate reproductive function and stress responses

A Mamgain, IL Sawyer, DAM Timajo… - Journal of …, 2021 - Soc Neuroscience
RF-amide related peptide 3 (RFRP-3) is a neuropeptide thought to inhibit central regulation
of fertility. We investigated whether alterations in RFRP neuronal activity led to changes in …

Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium

M Horazna, L Janeckova, J Svec, O Babosova… - Scientific Reports, 2019 - nature.com
The first step in the development of human colorectal cancer is aberrant activation of the Wnt
signaling pathway. Wnt signaling hyperactivation is predominantly caused by loss-of …

[PDF][PDF] Characterising the stress-related functions of RFRP neurons

IL Sawyer - 2022 - ourarchive.otago.ac.nz
Arginine-phenylalanine related-peptide (RFRP) neurons are a small population of neurons
found in and around the dorsomedial nucleus of the hypothalamus (DMH) in mammals …

The role of the Msx1 transcription factor in the intestinal epithelia and colorectal cancer

M Šťastná - 2019 - dspace.cuni.cz
The Wnt signaling pathway represents the principal evolutionarily conserved signaling
cascade found in all multicellular organisms. It plays a key role not only in many processes …