During hemolysis, erythrophagocytes dispose damaged red blood cells. This prevents the
extracellular release of hemoglobin, detoxifies heme, and recycles iron in a linked metabolic …

Reactive sulfur species (RSS) entail a diverse family of sulfur derivatives that have emerged
as important effector molecules in H 2 S-mediated biological events. RSS (including H 2 S) …

Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, which is
mainly characterized by lipid deposition and inflammatory response. Macrophages (MΦ), as …

Cell death is an important aspect of atherosclerotic plaque development. Insufficient
efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic …

Vulnerable atherosclerotic plaques with hemorrhage considerably contribute to
cardiovascular morbidity and mortality. Calcification is the main characteristic of advanced …

Heme degradation by the heme oxygenase (HMOX) family of enzymes is critical for
maintaining homeostasis and limiting heme-induced tissue damage. Macrophages express …

Background Intestinal mucositis (IM) is characterized by damage to the intestinal mucosa
resulting from inhibition of epithelial cell division and loss of renewal capacity following …

The aim of this study was to investigate whether CD74 levels in atherosclerotic lesions are
associated with inflammation, apoptosis, plaque severity, and clinical symptoms among …

Total body irradiation (TBI) can result in death associated with hematopoietic insufficiency.
Although radiation causes apoptosis of white blood cells, red blood cells (RBC) undergo …

Heme, the protoporphyrin IX iron complex is widely present in the human body and it is
involved in oxygen storage, electron transfer, and enzymatic reactions. However, free heme …