[HTML][HTML] The biology of lubricin: near frictionless joint motion

GD Jay, KA Waller - Matrix Biology, 2014 - Elsevier
Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an
important role in cartilage integrity. In healthy joints, lubricin molecules coat the cartilage …

Lubricants for osteoarthritis treatment: From natural to bioinspired and alternative strategies

H Yuan, LLE Mears, Y Wang, R Su, W Qi, Z He… - Advances in Colloid and …, 2023 - Elsevier
Osteoarthritis is the most common degenerative and highly prevalent joint disease,
characterized by progressive loss and destruction of articular cartilage. The damaged …

Surface-initiated self-healing of polymers in aqueous media

BK Ahn, DW Lee, JN Israelachvili, JH Waite - Nature materials, 2014 - nature.com
Polymeric materials that intrinsically heal at damage sites under wet or moist conditions are
urgently needed for biomedical and environmental applications,,,,,. Although hydrogels with …

The lubricated matter in body

H Yuan, W Cui - Progress in Materials Science, 2024 - Elsevier
Lubrication is everywhere in the body and essential for the correct operation of biological
systems when subjected to contact stress and wear. The body is like a continuously …

Strong adhesion and cohesion of chitosan in aqueous solutions

DW Lee, C Lim, JN Israelachvili, DS Hwang - Langmuir, 2013 - ACS Publications
Chitosan, a load-bearing biomacromolecule found in the exoskeletons of crustaceans and
insects, is a promising biopolymer for the replacement of synthetic plastic compounds. Here …

Bioinspired kirigami metasurfaces as assistive shoe grips

S Babaee, S Pajovic, A Rafsanjani, Y Shi… - Nature Biomedical …, 2020 - nature.com
Falls and subsequent complications are major contributors to morbidity and mortality,
especially in older adults. Here, by taking inspiration from claws and scales found in nature …

Bioinspired polymers for lubrication and wear resistance

V Adibnia, M Mirbagheri, J Faivre, J Robert… - Progress in Polymer …, 2020 - Elsevier
In this review, we discuss the concept of bioinspired lubrication using novel polymeric
structures, which has led to producing a myriad of new systems with effective and …

Cyclic polymer grafts that lubricate and protect damaged cartilage

G Morgese, E Cavalli, JG Rosenboom… - Angewandte …, 2018 - Wiley Online Library
Tissue‐reactive graft copolymers were designed to protect the cartilage against enzymatic
degradation and restore its lubrication properties during the early stages of osteoarthritis …

Boundary lubrication by adsorption film

J Zhang, Y Meng - Friction, 2015 - Springer
A complete understanding of the mechanism of boundary lubrication is a goal that scientists
have been striving to achieve over the past century. Although this complicated process has …

[HTML][HTML] The articular cartilage surface is impaired by a loss of thick collagen fibers and formation of type I collagen in early osteoarthritis

M Tschaikowsky, S Brander, V Barth, R Thomann… - Acta Biomaterialia, 2022 - Elsevier
Osteoarthritis (OA) is a joint disease affecting millions of patients worldwide. During OA
onset and progression, the articular cartilage is destroyed, but the underlying complex …