Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

RD Klein, SJ Hultgren - Nature Reviews Microbiology, 2020 - nature.com
Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

AL Flores-Mireles, JN Walker, M Caparon… - Nature reviews …, 2015 - nature.com
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range
of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus …

Urinary tract infection: pathogenesis and outlook

LK McLellan, DA Hunstad - Trends in molecular medicine, 2016 - cell.com
The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant
impact on millions of patients worldwide, most of whom are otherwise healthy women …

Recurrent urinary tract infection: a mystery in search of better model systems

BO Murray, C Flores, C Williams… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are among the most common infectious diseases worldwide
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …

Urinary tract infections in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

JD Goldman, K Julian - Clinical Transplantation, 2019 - Wiley Online Library
These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections

S Subramaniam, P Joyce, N Thomas… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Drug and vaccine development for the treatment and prevention of urinary tract infections

VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …

A human urothelial microtissue model reveals shared colonization and survival strategies between uropathogens and commensals

C Flores, J Ling, A Loh, RG Maset, A Aw, IJ White… - Science …, 2023 - science.org
Urinary tract infection is among the most common infections worldwide, typically studied in
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …

Non-surface attached bacterial aggregates: a ubiquitous third lifestyle

YM Cai - Frontiers in microbiology, 2020 - frontiersin.org
Bacteria are now generally believed to adopt two main lifestyles: planktonic individuals, or
surface-attached biofilms. However, in recent years medical microbiologists started to stress …