Vascularization in tissue engineering

J Rouwkema, NC Rivron, CA van Blitterswijk - Trends in biotechnology, 2008 - cell.com
Tissue engineering has been an active field of research for several decades now. However,
the amount of clinical applications in the field of tissue engineering is still limited. One of the …

Assessing identity, phenotype, and fate of endothelial progenitor cells

KK Hirschi, DA Ingram, MC Yoder - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
the Asahara at al10 article, human CD34 expressing cells (15.7% enriched for CD34
expression) in adult peripheral blood were interrogated as putative EPCs via in vitro and in …

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

S Purhonen, J Palm, D Rossi… - Proceedings of the …, 2008 - National Acad Sciences
The mechanisms by which bone marrow (BM)-derived stem cells might contribute to
angiogenesis and the origin of neovascular endothelial cells (ECs) are controversial …

High prevalence of KRAS/BRAF somatic mutations in brain and spinal cord arteriovenous malformations

T Hong, Y Yan, J Li, I Radovanovic, X Ma, YW Shao… - Brain, 2019 - academic.oup.com
Brain and spinal arteriovenous malformations are congenital lesions causing intracranial
haemorrhage or permanent disability especially in young people. We investigated whether …

[HTML][HTML] Endothelial progenitor cells in atherosclerosis

F Du, J Zhou, R Gong, X Huang… - … in bioscience: a …, 2012 - ncbi.nlm.nih.gov
Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial
homoeostasis and in the process of new vessel formation. Experimental and clinical studies …

Intra-arterial infusion of autologous bone marrow mononuclear cells in patients with moderate to severe middle cerebral artery acute ischemic stroke

MAG Friedrich, MP Martins, MD Araújo… - Cell …, 2012 - journals.sagepub.com
Transplantation of autologous bone marrow mononuclear cells (BMMCs) has been proven
safe in animal and human studies. However, there are very few studies in stroke patients. In …

Modeling cardiac disease mechanisms using induced pluripotent stem cell-derived cardiomyocytes: progress, promises and challenges

EI Parrotta, V Lucchino, L Scaramuzzino… - International Journal of …, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are a class of disorders affecting the heart or blood
vessels. Despite progress in clinical research and therapy, CVDs still represent the leading …

Bone marrow mononuclear cells promote proliferation of endogenous neural stem cells through vascular niches after cerebral infarction

A Nakano-Doi, T Nakagomi, M Fujikawa… - Stem …, 2010 - academic.oup.com
Increasing evidence shows that administration of bone marrow mononuclear cells (BMMCs)
is a potential treatment for various ischemic diseases, such as ischemic stroke. Although …

Endothelial progenitor cell: a blood cell by many other names may serve similar functions

MC Yoder - Journal of molecular medicine, 2013 - Springer
The first reports of circulating cells that displayed the capacity to repair and regenerate
damaged vascular endothelial cells as progenitor cells for the endothelial lineage (EPC) …

Endothelial injury and repair: a novel theory for atherosclerosis

E Mannarino, M Pirro - Angiology, 2008 - journals.sagepub.com
The traditional view of atherosclerosis as a pathological lipid deposition within the artery
wall has been redefined by a more complex theory in which the presence of a dysfunctional …