Cataracts

YC Liu, M Wilkins, T Kim, B Malyugin, JS Mehta - The Lancet, 2017 - thelancet.com
An estimated 95 million people worldwide are affected by cataract. Cataract still remains the
leading cause of blindness in middle-income and low-income countries. With the …

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

[HTML][HTML] Assessing the methods, tools, and statistical approaches in Google Trends research: systematic review

A Mavragani, G Ochoa, KP Tsagarakis - Journal of Medical Internet …, 2018 - jmir.org
Background In the era of information overload, are big data analytics the answer to access
and better manage available knowledge? Over the last decade, the use of Web-based data …

Posterior capsule opacification: What's in the bag?

IM Wormstone, YM Wormstone, AJO Smith… - Progress in Retinal and …, 2021 - Elsevier
Cataract, a clouding of the lens, is the most common cause of blindness in the world. It has a
marked impact on the wellbeing and productivity of individuals and has a major economic …

An artificial intelligence platform for the multihospital collaborative management of congenital cataracts

E Long, H Lin, Z Liu, X Wu, L Wang, J Jiang… - Nature biomedical …, 2017 - nature.com
Using artificial intelligence (AI) to prevent and treat diseases is an ultimate goal in
computational medicine. Although AI has been developed for screening and assisted …

Tissue repair and regeneration with endogenous stem cells

H Xia, X Li, W Gao, X Fu, RH Fang, L Zhang… - Nature Reviews …, 2018 - nature.com
In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …

Regenerating eye tissues to preserve and restore vision

JH Stern, Y Tian, J Funderburgh, G Pellegrini, K Zhang… - Cell stem cell, 2018 - cell.com
Ocular regenerative therapies are on track to revolutionize treatment of numerous blinding
disorders, including corneal disease, cataract, glaucoma, retinitis pigmentosa, and age …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens

Z Liu, S Huang, Y Zheng, T Zhou, L Hu, L Xiong… - Progress in retinal and …, 2023 - Elsevier
The crystalline lens is a transparent and refractive biconvex structure formed by lens
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …