Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely
aggressive malignancy associated with a poor overall prognosis. Women affected may vary …

Soft tissue sarcomas are a rare and multifaceted group of solid tumours. Neoadjuvant
chemotherapy is increasingly used to limit loss of function after wide surgical excision with …

Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

Background Previous trials from our group suggested an overall survival benefit with five
cycles of adjuvant full-dose epirubicin plus ifosfamide in localised high-risk soft-tissue …

Importance Patients with soft tissue sarcoma are at risk for local recurrence and distant
metastases despite optimal local treatment. Preoperative anthracycline plus ifosfamide …

Extraskeletal Ewing sarcoma is covered by other ESMO Guidelines: in general, the same
principles for these tumours in children apply to adults. This is also the case for embryonal …

Background The value of neoadjuvant chemotherapy in soft tissue sarcoma (STS) is not
completely understood. This study investigated the benefit of neoadjuvant chemotherapy …

Background This study was aimed at determining whether patients with high-risk soft tissue
sarcoma (STS), as identified using the nomogram Sarculator, benefitted from adjuvant …

The ability to activate drugs only at desired locations avoiding systemic immunosuppression
and other dose limiting toxicities is highly desirable. Here we present a new approach …

Purpose To assess the feasibility of grading soft tissue sarcomas (STSs) using MRI features
(radiomics). Materials and Methods MRI (echo planar SE, 1.5 T) from 19 patients with STSs …