The crossroads between RAS and RHO signaling pathways in cellular transformation, motility and contraction
O Soriano, M Alcón-Pérez, M Vicente-Manzanares… - Genes, 2021 - mdpi.com
Ras and Rho proteins are GTP-regulated molecular switches that control multiple signaling
pathways in eukaryotic cells. Ras was among the first identified oncogenes, and it appears …
pathways in eukaryotic cells. Ras was among the first identified oncogenes, and it appears …
Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking
K Yoshioka - Biochemical Society Transactions, 2021 - portlandpress.com
Phosphatidylinositol 3-kinases (PI3Ks) are critical regulators of many cellular processes
including cell survival, proliferation, migration, cytoskeletal reorganization, and intracellular …
including cell survival, proliferation, migration, cytoskeletal reorganization, and intracellular …
Structural basis of phosphatidylinositol 3-kinase C2α function
Abstract Phosphatidylinositol 3-kinase type 2α (PI3KC2α) is an essential member of the
structurally unresolved class II PI3K family with crucial functions in lipid signaling …
structurally unresolved class II PI3K family with crucial functions in lipid signaling …
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
WT Lo, H Belabed, M Kücükdisli, J Metag… - Nature chemical …, 2023 - nature.com
Abstract Phosphatidylinositol 3-kinase type 2α (PI3KC2α) and related class II PI3K isoforms
are of increasing biomedical interest because of their crucial roles in endocytic membrane …
are of increasing biomedical interest because of their crucial roles in endocytic membrane …
Collagen from Iris squid grafted with polyethylene glycol and collagen peptides promote the proliferation of fibroblast through PI3K/AKT and Ras/RAF/MAPK signaling …
C Hou, Y Lei, N Li, M Wei, S Wang, SU Rahman… - International Journal of …, 2023 - Elsevier
Collagens from marine sources have been used widely in food, cosmetics and tissue
engineering application due to their excellent functional and biological properties. In the …
engineering application due to their excellent functional and biological properties. In the …
The molecular mechanisms mediating class II PI 3‐kinase function in cell physiology
PA Koch, GL Dornan, M Hessenberger… - The FEBS …, 2021 - Wiley Online Library
The phosphoinositide 3‐kinase (PI3K) family of lipid‐modifying enzymes plays vital roles in
cell signaling and membrane trafficking through the production of 3‐phosphorylated …
cell signaling and membrane trafficking through the production of 3‐phosphorylated …
An overview of class II phosphoinositide 3-kinases
EYZ Heng, T Maffucci - PI3K and AKT Isoforms in Immunity: Mechanisms …, 2022 - Springer
Abstract Phosphoinositide 3-kinases (PI3Ks) catalyse the synthesis of specific members of
the family of lipids collectively known as 'phosphoinositides'. These PI3Ks products can in …
the family of lipids collectively known as 'phosphoinositides'. These PI3Ks products can in …
Repurposing inhibitors of phosphoinositide 3-kinase as adjuvant therapeutics for bacterial infections
R Fleeman - Frontiers in Antibiotics, 2023 - frontiersin.org
The rise in antimicrobial resistance and the decline in new antibiotics has created a great
need for novel approaches to treat drug resistant bacterial infections. Increasing the burden …
need for novel approaches to treat drug resistant bacterial infections. Increasing the burden …
PI3K 信号通路调控动脉粥样硬化发生发展的研究进展
刘珍竹， 李靖， 何丹， 曲鹏 - 基础医学与临床, 2022 - journal11.magtechjournal.com
短篇综述PI3K信号通路调控动脉粥样硬化发生发展的研究进展 Page 1 2022年9月 第42卷第9期
基础医学与临床 Basic and Clinical Medicine September 2022 Vol.42 No.9 收稿日期:2021⁃02⁃09 …
基础医学与临床 Basic and Clinical Medicine September 2022 Vol.42 No.9 收稿日期:2021⁃02⁃09 …
Control of integrin adhesions by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model
P Samsó Ferré - 2023 - refubium.fu-berlin.de
Myotubuläre Myopathie (X-linked centrouclear myopathy; XLCNM) ist eine seltene und
schwere Skelettmuskelerkrankung, die sich mit angeborener Hypotonie manifestiert und zu …
schwere Skelettmuskelerkrankung, die sich mit angeborener Hypotonie manifestiert und zu …