In recent years the emergence and resurgence of arboviruses have generated a global
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …

The vector-borne flaviviruses cause severe disease in humans on every inhabited continent
on earth. Their transmission by arthropods, particularly mosquitoes, facilitates large …

Flaviviruses are known to cause a variety of diseases in humans in different parts of the
world. There are very limited numbers of antivirals to combat flavivirus infection, and …

Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …

West Nile virus (WNV) is an emerging zoonotic mosquito-borne flavivirus responsible for
outbreaks of febrile illness and meningoencephalitis. The replication of WNV takes place on …

Dengue virus is an arbovirus belonging to class Flaviviridae Its clinical manifestation ranges
from asymptomatic to extreme conditions (dengue hemorrhagic fever/dengue shock …

Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …

Lipids are necessary for every step in the replication cycle of hepatitis C virus (HCV) and
dengue virus (DENV), members of the family Flaviviridae. Recent studies have …

Highlights•Detailed structural models are available for Flavivirus NS5 and NS3
proteins.•Complex structures of NS5 and NS3 with NTP and RNA substrates and regulatory …

The placenta is a highly specialized organ that is formed during human gestation for
conferring protection and generating an optimal microenvironment to maintain the …