Hepatitis D virus: introduction and epidemiology

M Rizzetto - Cold Spring Harbor perspectives in …, 2015 - perspectivesinmedicine.cshlp.org
Hepatitis D is caused by the hepatitis D virus (HDV), a unique RNA pathogen that requires
the hepatitis B surface antigen (HBsAg) to infect. Hepatitis D is transmitted by the parenteral …

Hepatitis delta virus: insights into a peculiar pathogen and novel treatment options

FA Lempp, Y Ni, S Urban - Nature reviews Gastroenterology & …, 2016 - nature.com
Chronic hepatitis D is the most severe form of viral hepatitis, affecting∼ 20 million HBV-
infected people worldwide. The causative agent, hepatitis delta virus (HDV), is a unique …

Hepatitis delta: virological and clinical aspects

LF Botelho-Souza, MPA Vasconcelos, AO Dos Santos… - Virology journal, 2017 - Springer
There are an estimated 400 million chronic carriers of HBV worldwide; between 15 and 20
million have serological evidence of exposure to HDV. Traditionally, regions with high rates …

Pathogenesis of and new therapies for hepatitis D

C Koh, T Heller, JS Glenn - Gastroenterology, 2019 - Elsevier
Hepatitis delta virus (HDV) infection of humans was first reported in 1977, and now it is now
estimated that 15–20 million people are infected worldwide. Infection with HDV can be an …

Delta hepatitis within the Veterans Affairs medical system in the United States: prevalence, risk factors, and outcomes

T Kushner, M Serper, DE Kaplan - Journal of hepatology, 2015 - Elsevier
Background & Aims Low hepatitis delta prevalence estimates in the United States are likely
biased due to low testing rates. The objectives of this study were to quantify the prevalence …

Hepatitis delta: epidemiology, diagnosis and management 36 years after discovery

M Noureddin, R Gish - Current gastroenterology reports, 2014 - Springer
With recent studies showing increased prevalence of hepatitis delta (HDV) even in the US,
Australia, and some countries in Europe, and very high prevalence in endemic regions, HDV …

Clinical and virological heterogeneity of hepatitis delta in different regions world‐wide: the Hepatitis Delta International Network (HDIN)

A Wranke, LM Pinheiro Borzacov, R Parana… - Liver …, 2018 - Wiley Online Library
Abstract Background & Aims Chronic hepatitis D (delta) is a major global health burden.
Clinical and virological characteristics of patients with hepatitis D virus (HDV) infection and …

[HTML][HTML] Hepatitis B virus/hepatitis D virus epidemiology: Changes over time and possible future influence of the SARS-CoV-2 pandemic

C Sagnelli, M Pisaturo, C Curatolo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Hepatitis D virus (HDV) is a defective liver-tropic virus that needs the helper function of
hepatitis B virus (HBV) to infect humans and replicate. HDV is transmitted sexually or by a …

Hepatitis delta virus: From biological and medical aspects to current and investigational therapeutic options

D Alfaiate, P Dény, D Durantel - Antiviral research, 2015 - Elsevier
An estimated 15–20 million individuals are co-infected by hepatitis B and hepatitis D virus
worldwide and are at high risk of developing end-stage liver disease, including …

[HTML][HTML] Hepatitis delta: Current knowledge and future directions

M Lange, D Zaret, T Kushner - Gastroenterology & Hepatology, 2022 - ncbi.nlm.nih.gov
Hepatitis delta virus (HDV) infection is caused by a unique circular RNA virus that relies on
both the hepatitis B virus (HBV) antigen and human host polymerases for its transmission …