Cell signalling engenders cells with the capability to receive and process information from
the intracellular and extracellular environments, trigger and execute biological responses …

Targeted and specific induction of cell death in an individual or groups of cells hold the
potential for new insights into the response of tissues or organisms to different forms of …

BRAF is prototypical of oncogenes that can be targeted therapeutically and the treatment of
BRAFV600E melanomas with RAF and MEK inhibitors results in rapid tumor regression …

The signaling events controlling proliferation, survival, and apoptosis during mammary
epithelial acinar morphogenesis remain poorly characterized. By imaging single-cell ERK …

Optogenetics has become a key tool to manipulate biological processes with high spatio-
temporal resolution. Recently, a number of commercial and open-source multi-well …

Signaling is central in cell fate regulation, and relevant information is encoded in its activity
over time (ie, dynamics). However, simultaneous dynamics quantification of several …