Pyridine compounds with antimicrobial and antiviral activities

M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …

1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications

A Donaire-Arias, AM Montagut, R Puig de la Bellacasa… - Molecules, 2022 - mdpi.com
Pyrazolo [3, 4-b] pyridines are a group of heterocyclic compounds presenting two possible
tautomeric forms: the 1 H-and 2 H-isomers. More than 300,000 1 H-pyrazolo [3, 4-b] …

Discovery of novel pyrazolo [3, 4-b] pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells

MS Nafie, AM Amer, AK Mohamed… - Bioorganic & Medicinal …, 2020 - Elsevier
Pim-1 kinase targeted recently has proved an essential goal of breast cancer therapy. We
report the design, synthesis with full characterization analysis of pyrazolo [3, 4-b] pyridine …

Recent progress in anticancer agents incorporating pyrazole scaffold

S Mor, M Khatri, R Punia… - Mini Reviews in Medicinal …, 2022 - benthamdirect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …

Cyanothioacetamide: a polyfunctional reagent with broad synthetic utility

VD Dyachenko, IV Dyachenko… - Russian Chemical …, 2018 - iopscience.iop.org
The review integrates and analyzes the published data on the chemical reactivity of α-
cyanothioacetamide, a convenient starting compound for the preparation of activated …

Anticancer evaluation and molecular docking of new pyridopyrazolo-triazine and pyridopyrazolo-triazole derivatives

MR Elmorsy, E Abdel-Latif, HE Gaffer, SE Mahmoud… - Scientific Reports, 2023 - nature.com
Amino-4, 6-dimethylpyrazolopyridine was applied as a precursor for the synthesis of some
new pyridopyrazolo-triazine and pyridopyrazolo-triazole derivatives through diazotization …

Magnetically separable graphene oxide anchored sulfonic acid: a novel, highly efficient and recyclable catalyst for one-pot synthesis of 3, 6-di (pyridin-3-yl)-1 H …

M Zhang, P Liu, YH Liu, ZR Shang, HC Hu, ZH Zhang - RSC advances, 2016 - pubs.rsc.org
Magnetically separable graphene oxide anchored sulfonic acid (Fe3O4–GO–SO3H)
nanoparticles were prepared and characterized by X-ray diffraction (XRD), scanning …

5-Amino-pyrazoles: potent reagents in organic and medicinal synthesis

A Shaabani, MT Nazeri, R Afshari - Molecular diversity, 2019 - Springer
Amino-pyrazoles have proven to be a class of fascinating and privileged organic tools for the
construction of diverse heterocyclic or fused heterocyclic scaffolds. This review presents …

Discovery of new pyrazolopyridine, furopyridine, and pyridine derivatives as CDK2 inhibitors: Design, synthesis, docking studies, and anti-proliferative activity

AAH Abdel-Rahman, AKF Shaban, IF Nassar… - Molecules, 2021 - mdpi.com
New pyridine, pyrazoloyridine, and furopyridine derivatives substituted with naphthyl and
thienyl moieties were designed and synthesized starting from 6-(naphthalen-2-yl)-2-oxo-4 …

Magnetically separable transition metal ferrites: versatile heterogeneous nano‐catalysts for the synthesis of diverse bioactive heterocycles

G Kaur, P Devi, S Thakur, A Kumar, R Chandel… - …, 2019 - Wiley Online Library
Magnetically Separable Transition Metal Ferrites: Versatile Heterogeneous Nano‐Catalysts
for the Synthesis of Diverse Bioactive Heterocycles - Kaur - 2019 - ChemistrySelect - Wiley …