Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
Marine algae: A treasure trove of bioactive anti-inflammatory compounds
This comprehensive review examines the diverse classes of pharmacologically active
compounds found in marine algae and their promising anti-inflammatory effects. The review …
compounds found in marine algae and their promising anti-inflammatory effects. The review …
The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products
Starting from vanillin, known four benzyl bromides with Br were synthesized. The first
synthesis of natural product 3, 4-dibromo-5-((methylsulfonyl) methyl) benzene-1, 2-diol (2) …
synthesis of natural product 3, 4-dibromo-5-((methylsulfonyl) methyl) benzene-1, 2-diol (2) …
Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives
In this study, series of novel bromophenol derivatives were synthesized and investigated for
their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were …
their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were …
Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties
M Boztas, Y Cetinkaya, M Topal, I Gulcin… - Journal of medicinal …, 2015 - ACS Publications
Cyclopropylcarboxylic acids and esters and cyclopropylmethanols incorporating
bromophenol moieties were investigated as inhibitors of the carbonic anhydrase enzyme …
bromophenol moieties were investigated as inhibitors of the carbonic anhydrase enzyme …
Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions
In this study, a series of novel bromophenols were synthesized from benzoic acids and
methoxylated bromophenols. The synthesized compounds were evaluated by using different …
methoxylated bromophenols. The synthesized compounds were evaluated by using different …
Synthesis, Antioxidant, and Antiacetylcholinesterase Activities of Sulfonamide Derivatives of Dopamine‐R elated Compounds
A series of sulfonamides were synthesized from dopamine derivatives. The reactions of
amines with methanesulfonyl chloride followed by O‐demethylation with BBr3 afforded …
amines with methanesulfonyl chloride followed by O‐demethylation with BBr3 afforded …
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II
Sulfonamides represent a significant class of biologically active compounds that inhibit
carbonic anhydrase (CA, EC.: 4.2. 1.1) isoenzymes involved in different pathological and …
carbonic anhydrase (CA, EC.: 4.2. 1.1) isoenzymes involved in different pathological and …
The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase …
The first synthesis of (E)-4-(3-bromo-4, 5-dihydroxyphenyl) but-3-en-2-one (1),(E)-4-(2-
bromo-4, 5-dihydroxyphenyl) but-3-en-2-one (2), and (E)-4-(2, 3-dibromo-4, 5 …
bromo-4, 5-dihydroxyphenyl) but-3-en-2-one (2), and (E)-4-(2, 3-dibromo-4, 5 …
Capsaicin: a potent inhibitor of carbonic anhydrase isoenzymes
B Arabaci, I Gulcin, S Alwasel - Molecules, 2014 - mdpi.com
Carbonic anhydrase (CA, EC 4.2. 1.1) is a zinc containing metalloenzyme that catalyzes the
rapid and reversible conversion of carbon dioxide (CO2) and water (H2O) into a proton (H+) …
rapid and reversible conversion of carbon dioxide (CO2) and water (H2O) into a proton (H+) …