Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Space programmes are shifting toward planetary exploration, and in particular towards
missions by human beings to the moon and Mars. However, exposure to space radiation is …

Interactions between ends from different DNA double-strand breaks (DSBs) can produce
tumorigenic chromosome translocations. Two theories for the juxta-position of DSBs in …

The concept of DNA “repair centers” and the meaning of radiation-induced foci (RIF) in
human cells have remained controversial. RIFs are characterized by the local recruitment of …

Radiotherapy (ionising radiation; IR) is utilised in the treatment of~ 50% of all human
cancers, and where the therapeutic effect is largely achieved through DNA damage …

Protontherapy is a rapidly expanding radiotherapy modality where accelerated proton
beams are used to precisely deliver the dose to the tumor target but is generally considered …

Abstract Cucinotta, FA, Kim, MH. Y., Willingham, V. and George, KA Physical and Biological
Organ Dosimetry Analysis for International Space Station Astronauts. Radiat. Res. 170, 127 …

Abstract Knowledge about established breast carcinogens can support improved and
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …

Genomes are housed within cell nuclei as individual chromosome territories. Nuclei contain
several architectural structures that interact and influence the genome. In this review, we …