Network structure of the master clock is important for its primary function

C Gu, J Li, J Zhou, H Yang, J Rohling - Frontiers in Physiology, 2021 - frontiersin.org
A master clock located in the suprachiasmatic nucleus (SCN) regulates the circadian rhythm
of physiological and behavioral activities in mammals. The SCN has two main functions in …

[HTML][HTML] Heterogeneity of neuronal properties determines the collective behavior of the neurons in the suprachiasmatic nucleus

C Gu, P Wang, T Weng, H Yang… - Mathematical Biosciences …, 2019 - aimspress.com
Circadian rhythms have been observed in behavioral and physiological activities of living
things exposed to the natural 24 h light-darkness cycle. Interestingly, even under constant …

Measuring relative coupling strength in circadian systems

C Schmal, ED Herzog, H Herzel - Journal of biological …, 2018 - journals.sagepub.com
Modern imaging techniques allow the monitoring of circadian rhythms of single cells.
Coupling between these single cellular circadian oscillators can generate coherent periodic …

Robust features of chimera states and the implementation of alternating chimera states

R Ma, J Wang, Z Liu - Europhysics Letters, 2010 - iopscience.iop.org
It is well known that different from most mammals with bihemispheric sleep, birds, some
aquatic mammals, and reptiles engage in unihemispheric sleep to mitigate the fundamental …

Positive and negative couplings perform complementary roles in the signal amplification of globally coupled bistable oscillators

X Liang, C Liu, X Zhang - Physical Review E, 2020 - APS
We investigate a system of globally coupled bistable oscillators subjected to a common
weak signal, where the couplings are oscillator dependent with random signs: positive or …

The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus

C Gu, A Ramkisoensing, Z Liu… - Journal of biological …, 2014 - journals.sagepub.com
In mammals, the central clock in the suprachiasmatic nucleus (SCN) controls physiological
and behavioral circadian rhythms and is entrained to the external light-dark cycle. The ability …

Impact of dispersed coupling strength on the free running periods of circadian rhythms

C Gu, JHT Rohling, X Liang, H Yang - Physical Review E, 2016 - APS
The dominant endogenous clock, named the suprachiasmatic nucleus (SCN), regulates
circadian rhythms of behavioral and physiological activity in mammals. One of the main …

The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods

C Gu, M Tang, H Yang - Scientific Reports, 2016 - nature.com
The main function of the principal clock located in the suprachiasmatic nucleus (SCN) of
mammals is synchronizing the body rhythms to the 24 h light-dark cycle. Additionally, the …

Photic desynchronization of two subgroups of circadian oscillators in a network model of the suprachiasmatic nucleus with dispersed coupling strengths

C Gu, Z Liu, WJ Schwartz, P Indic - PLoS One, 2012 - journals.plos.org
The suprachiasmatic nucleus (SCN) is the master circadian clock in mammals and is
composed of thousands of neuronal oscillators expressing different intrinsic periods. These …

Heterogeneity induces rhythms of weakly coupled circadian neurons

C Gu, X Liang, H Yang, JHT Rohling - Scientific reports, 2016 - nature.com
The main clock located in the suprachiasmatic nucleus (SCN) regulates circadian rhythms in
mammals. The SCN is composed of approximately twenty thousand heterogeneous self …