Simple Summary In the process of production, especially the modern intensive scale farming
where high quality and high efficiency are pursued, pigs are subjected to a series of adverse …

Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease
(NAFLD) characterized by liver steatosis, inflammation, and hepatocellular damage. NASH …

5′-Adenosine monophosphate–activated protein kinase (AMPK) is a master regulator of
energy homeostasis in eukaryotes. Despite three decades of investigation, the biological …

AMP kinase is a heterotrimeric serine/threonine protein kinase that regulates a number of
metabolic processes, including lipid biosynthesis and metabolism. AMP kinase activity is …

This review will examine the role of 5′-adenosine monophosphate-activated protein kinase
(AMPK) in the treatment of obesity, medical nutrition and chronic diseases, and its …

Type 2 diabetes mellitus is a complex metabolic disorder requiring polypharmacology
approaches for effective treatment. Combinatorial library of fifteen new tricyclic …

Abstract Dysregulation of 5′-adenosine monophosphate-activated protein kinase (AMPK)
occurs in metabolic disorders including non-alcoholic fatty liver disease (NAFLD) which …

Thymoquinone (TQ) is a biologically active compound isolated from the seeds of Nigella
sativa L.(Ranuculaceae). This study investigated the hepato-protective effect of TQ on liver …

5′-Adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of
mammalian energy homeostasis and has been implicated in mediating many of the …

Heat stress causes reversible changes in tight junction proteins in immature Sertoli cells via
inhibition of the AMPK signaling pathway; these effects are accompanied by an increase in …