Neurotransmitters—key factors in neurological and neurodegenerative disorders of the central nervous system
Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …
an essential role in information transmission throughout the nervous system. Hundreds of …
Applications of various types of nanomaterials for the treatment of neurological disorders
Neurological disorders (NDs) are recognized as one of the major health concerns globally.
According to the World Health Organization (WHO), neurological disorders are one of the …
According to the World Health Organization (WHO), neurological disorders are one of the …
A comprehensive review of advanced focused ultrasound (FUS) microbubbles-mediated treatment of Alzheimer's disease
Alzheimer's disease (AD) is characterized by progressive neurodegeneration, memory loss,
and cognitive impairment leading to dementia and death. The blood-brain barrier (BBB) …
and cognitive impairment leading to dementia and death. The blood-brain barrier (BBB) …
AGE-RAGE axis culminates into multiple pathogenic processes: A central road to neurodegeneration
R Bhattacharya, MR Alam, MA Kamal… - Frontiers in Molecular …, 2023 - frontiersin.org
Advanced glycation end-products (AGEs; eg, glyoxal, methylglyoxal or carboxymethyl-
lysine) are heterogenous group of toxic compounds synthesized in the body through both …
lysine) are heterogenous group of toxic compounds synthesized in the body through both …
Evaluating the role of N-Acetyl-L-Tryptophan in the Aβ 1-42-induced neuroinflammation and cognitive decline in Alzheimer's disease
Abstract Alzheimer's disease (AD), a neurodegenerative condition previously known to affect
the older population, is also now seen in younger individuals. AD is often associated with …
the older population, is also now seen in younger individuals. AD is often associated with …
Nanomaterials that Aid in the Diagnosis and Treatment of Alzheimer's Disease, Resolving Blood–Brain Barrier Crossing Ability
Q Song, J Li, T Li, HW Li - Advanced Science, 2024 - Wiley Online Library
As a form of dementia, Alzheimer's disease (AD) suffers from no efficacious cure, yet AD
treatment is still imperative, as it ameliorates the symptoms or prevents it from deteriorating …
treatment is still imperative, as it ameliorates the symptoms or prevents it from deteriorating …
Exploitation of marine molecules to manage alzheimer's disease
Neurodegenerative diseases are sociosanitary challenges of today, as a result of increased
average life expectancy, with Alzheimer's disease being one of the most prevalent. This …
average life expectancy, with Alzheimer's disease being one of the most prevalent. This …
Mitochondrial Complex I and β-Amyloid Peptide Interplay in Alzheimer's Disease: A Critical Review of New and Old Little Regarded Findings
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the main
cause of dementia which is characterized by a progressive cognitive decline that severely …
cause of dementia which is characterized by a progressive cognitive decline that severely …
Mechanisms involved in microglial-interceded Alzheimer's disease and nanocarrier-based treatment approaches
Alzheimer's disease (AD) is a common neurodegenerative disorder accountable for
dementia and cognitive dysfunction. The etiology of AD is complex and multifactorial in …
dementia and cognitive dysfunction. The etiology of AD is complex and multifactorial in …
Synthesis and biological evaluation of benzimidazoles/1, 3, 5-triazine-2, 4-diamine hybrid compounds: a new class of multifunctional alzheimer targeting agents
In this study, a series of new benzimidazole/1, 3, 5-triazine-2, 4-diamine hybrid derivatives
(9a–9l) were designed and synthesized. The potential multi-target profiles of these …
(9a–9l) were designed and synthesized. The potential multi-target profiles of these …